Imidazo(1,2-a)pyrimidines and their salts, process and intermediates for their preparation, their use as medicaments and compositions containing them

Abstract

Abstract Translated from French L'invention a pour objet les nouvelles imidazo/1,2-a/pyrimidines I : <IMAGE> où R est un alcoyle (1-8C), un alcényle (2-8C), un cycloalcoyle (3-7C), un cycloalcoylalcoyle (4-12C), un aryle (6-12C), un thiényle ou pyridyle, éventuellement substitué R1 et R2 représentent un hydrogène, un alcoyle (1-8C), un alcényle (2-5C), un cycloalcoyle (3-7C), un cycloalcoylalcoyle (4-12C), un benzyle ou un phénéthyle, ou R1 et R2 forment un alcoylène (3-5C), R1 et R2 pouvant être substitués, X est un oxygène ou un soufre, R3 est un alcoyle (1-5C), ainsi que leurs sels d'acides, leur procédé et leurs intermédiaires de préparation, leur application comme médicaments, notamment anxiolytiques et les compositions les renfermant. The subject of the invention is the new imidazo / 1,2-a / pyrimidines I: <IMAGE> where R is an alkyl (1-8C), an alkenyl (2-8C), a cycloalkyl (3-7C), a cycloalkylalkyl (4-12C), aryl (6-12C), thienyl or pyridyl, optionally substituted R1 and R2 represent hydrogen, alkyl (1-8C), alkenyl (2-5C), cycloalkyl (3- 7C), a cycloalkylalkyl (4-12C), a benzyl or a phenethyl, or R1 and R2 form an alkylene (3-5C), R1 and R2 can be substituted, X is an oxygen or a sulfur, R3 is an alkyl ( 1-5C), as well as their acid salts, their process and their preparation intermediates, their application as medicaments, in particular anxiolytics and the compositions containing them.

Inventors

• 👤 Wilfred Roger Tully

Bibliographic Details