Patent EP0230579A1 successfully refreshed from Google Patents.
EP0111904A2
Expired / Lapsed
EP
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Propynylaminothiazole derivatives
Assignee: Shionogi and Co Ltd
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Filing: 1983-12-15
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Granted: —
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Expires: 2003-12-15
Abstract
Abstract New 2-(2-propynylamino)thiazole and 2-(3-iodo-2-propynylamino)thiazole derivatives having anti-microbial activity which are used as an active ingredient in anti-microbial compositions for medical and agricultural use.
Inventors
- 👤 Yasuo Makisumi
- 👤 Akira Murabayashi
- 👤 Katsuya Tawara
- 👤 Yoshihachi Watanabe
- 👤 Toshio Takahashi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-05 09:51
CPC Classifications
C; C07; C07D; C07D277/00; C07D277/60; C07D277/62; C07D277/68; C07D277/82; A; A61; A61P; A61P31/00; A61P31/04; A61P31/10; C07D277/02; C07D277/20; C07D277/32; C07D277/38; C07D277/42; C07D277/56
Claims Analysis
Total Claims: 26
Claim 1
Independent Claim
119 words
A compound of the formula I : wherein R 1 is hydrogen, Cl-4 alkyl, carb oxy, formyl, hydroxy-C 1-4 alkyl, mono- or di-C 1-4 alkyl-aminomethyl, C 1-4 alkoxy-carbonyl, hydroxyiminomethyl, phenyl or wherein Y is hydrogen or C 1-4 alkyl and Z is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, hydroxy-C 1-4 alkyl or carboxy- C 1-4 alkyl; R 2 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy-carbonyl or halogen; R and R 2 when taken together with the attached carbons are a condensed benzene ring optionally substituted by 1 or 2 groups selected from the group consisting of C 1-4 alkyl and C 1-4 alkoxy; R 3 is hydrogen or C 1-4 alkyl; and X is hydrogen or iodine.
Claim 2
Dependent Claim
119 words
A compound of the formula I : wherein R 1 is hydrogen, Cl-4 alkyl, carb oxy, formyl, hydroxy-C 1-4 alkyl, mono- or di-C 1-4 alkyl-aminomethyl, C 1-4 alkoxy-carbonyl, hydroxyiminomethyl, phenyl or wherein Y is hydrogen or C 1-4 alkyl and Z is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, hydroxy-C 1-4 alkyl or carboxy- C 1-4 alkyl; R 2 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy-carbonyl or halogen; R and R 2 when taken together with the attached carbons are a condensed benzene ring optionally substituted by 1 or 2 groups selected from the group consisting of C 1-4 alkyl and C 1-4 alkoxy; R 3 is hydrogen or C 1-4 alkyl; and X is hydrogen or iodine.
Claim 3
Dependent Claim
16 words
The compound claimed in claim I wherein R 1 is hydrogen, C 1-4 alkyl or phenyl.
Claim 4
Dependent Claim
14 words
The compound claimed in claim 1 wherein R 1 is hydrogen., methyl or phenyl.
Claim 5
Dependent Claim
16 words
The compound claimed in claim 1 wherein R 2 is hydrogen, C 1-4 alkyl or halogen.
Claim 6
Dependent Claim
16 words
The compound claimed in claim 1 wherein R 2 is hydrogen, methyl, ethyl, propyl or chlorine.
Claim 7
Dependent Claim
26 words
The compound claimed in claim 1 wherein R 1 and R 2 when taken together with the attached carbons form benzene, methylbenzene, dimethylbenzene, methoxybenzene, or dimethoxybenzene.
Claim 8
Dependent Claim
24 words
The compound claimed in claim 1 wherein R 1 and R 2 when taken together with the attached carbons form benzene, 6-methylbenzene or 4,5-dimethylbenzene.
Claim 9
Dependent Claim
15 words
The compound claimed in claim 1 wherein R 3 is hydrogen, methyl, ethyl or propyl.
Claim 10
Dependent Claim
13 words
The compound claimed in claim 1 wherein R 3 is hydrogen or methyl.
Claim 11
Dependent Claim
25 words
The compound claimed in claim 2 wherein R 2 is hydrogen, C 1-4 alkyl or halogen and R 3 is hydrogen, methyl, ethyl or propyl.
Claim 12
Dependent Claim
23 words
The compound claimed in claim 3 wherein R 2 is hydrogen, methyl, ethyl, propyl or chlorine and R 3 is hydrogen or methyl.
Claim 13
Dependent Claim
15 words
The compound claimed in claim 6 wherein R 3 is hydrogen, methyls ethyl or propyl.
Claim 14
Dependent Claim
13 words
The compound claimed in claim 7 wherein R 3 is hydrogen or methyl.
Claim 15
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-5-methylthiazole.
Claim 16
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)benzothiazole.
Claim 17
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(3-iodo-2-propynylamino)benzothiazole.
Claim 18
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-5-ethylthiazole.
Claim 19
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-5-propylthiazole.
Claim 20
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-4-methylthiazole.
Claim 21
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-4-methylbenzothiazole.
Claim 22
Dependent Claim
8 words
The compound claimed in claim 1 is 2-(N-methyl-3-iodo-2-propynylamino)-5,6-dimethylbenzothiazole.
Claim 23
Dependent Claim
23 words
An anti-microbial composition for medical use which comprises containing the compound claimed in claim I as an active ingredient with a suitable adjuvant.
Claim 24
Dependent Claim
15 words
The composition claimed in claim 22 which contains an effective amount of the active ingredient.
Claim 25
Dependent Claim
23 words
An anti-microbial composition for agricultural use which comprises containing the compound claimed in claim 1 as an active ingredient with a suitable adjuvant.
Claim 26
Dependent Claim
15 words
The composition claimed in claim 24 which contains an effective amount of the active ingredient.
References Cited (Backward Citations)
No citation records indexed.
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