EP0123291A2
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EP
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Method for stabilizing interferon
Assignee: KH Neochem Co Ltd
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Filing: 1984-04-19
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Granted: —
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Expires: 2004-04-19
Abstract
Abstract A method for stabilizing interferon which involves the addition of an alkali metal salt or magnesium chloride to interferon as a stabilizer. The stability of the interferon may be further enhanced by the addition of serum albumin and by freeze-drying. Also, a method for stabilizing interferon which comprises bringing interferon into contact with a saccharide that is selected from the group consisting of dextran, chondroitin sulfuric acid, starch, glycogen, inulin, dextrin and alginic acid salt.
Inventors
- 👤 Yasuki Kato
- 👤 Rie Ohshima
- 👤 Naoko Tanaka
- 👤 Eiji Hayakawa
- 👤 Masuo Moriyama
- 👤 Akira Kondo
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-29 09:08
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/19; A61K38/21; A61K38/215; A61K47/00; A61K47/02; A61K47/30; A61K47/36; A61K47/42
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
44 words
A method for stabilizing interferon which comprises bringing an interferon into contact with a stabilizing agent containing an alkali metal salt, magnesium chloride or a saccharide selected from the group consisting of dextran, chondroitin sulfuric acid, starch, glycogen, inulin, dextrin and alginic acid salt.
Claim 2
Independent Claim
44 words
A method for stabilizing interferon which comprises bringing an interferon into contact with a stabilizing agent containing an alkali metal salt, magnesium chloride or a saccharide selected from the group consisting of dextran, chondroitin sulfuric acid, starch, glycogen, inulin, dextrin and alginic acid salt.
Claim 3
Dependent Claim
19 words
The method according to claim 2, wherein the stabilizing agent is a serum albumin and an alkali metal salt.
Claim 4
Dependent Claim
22 words
The method according to claim 1 wherein the stabilizing agent is a saccharide defined in claim 1 and an alkali metal salt.
Claim 5
Dependent Claim
28 words
The method according to claim 1, 2 or 3, wherein the alkali metal salt is selected from the group consisting of sodium chloride, potassium chloride and lithium chloride.
Claim 6
Dependent Claim
22 words
The method according to claim 1, wherein the interferon is selected from the group consisting of Interferon- , Interferon- and Interferon- .
Claim 7
Dependent Claim
33 words
The method according to claim 1, wherein the amount of the alkali metal salt admixed with the interferon is 1 x 10 -11 - 3 x 10 -10 mole per unit of interferon.
Claim 8
Dependent Claim
30 words
The method according to claim 1, wherein the amount of saccharide admixed with the interferon is 5 x 10 -14 - 4 x 10 -12 mole per unit of interferon.
Claim 9
Dependent Claim
36 words
A composition which contains an interferon and a stabilizing agent containing alkali metal salt, magnesium chloride or saccharide selected from the group consisting of dextran, chondroitin sulfuric acid, starch, glycogen, inulin, dextrin and alginic acid salt.
Claim 10
Dependent Claim
36 words
A composition which contains an interferon and a stabilizing agent containing alkali metal salt, magnesium chloride or saccharide selected from the group consisting of dextran, chondroitin sulfuric acid, starch, glycogen, inulin, dextrin and alginic acid salt.
Claim 11
Dependent Claim
19 words
The composition according to claim 8, wherein the stabilizing agent is a serum albumin and an alkali metal salt.
Claim 12
Dependent Claim
22 words
The composition according to claim 8, wherein the stabilizing agent is a saccharide defined in claim 8 and an alkali metal salt.
Claim 13
Dependent Claim
28 words
The composition according to claim 8, 9 or 10, wherein the alkali metal salt is selected from the group consisting of sodium chloride, potassium chloride and lithium chloride.
Claim 14
Dependent Claim
22 words
The composition according to claim 8, wherein the interferon is selected from the group consisting of Interferon- , Interferon- and Interferon- .
Claim 15
Dependent Claim
33 words
The composition according to claim 8, wherein the amount of the alkali metal salt admixed with the interferon is 1 x 10 -11 - 3 x 10 -10 mole per unit of interferon.
Claim 16
Dependent Claim
29 words
The composition according to claim 8, wherein the amount of saccharide admixed with the interferon is 5 x 10 -14 - 4 x 10-12 mole per unit of interferon.
References Cited (Backward Citations)
No citation records indexed.
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