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EP0141607A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Improved method for enxymatic cleaning and disinfecting contact lenses

Assignee: Bausch and Lomb Inc
•
Filing: 1984-10-22
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Granted: —
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Expires: 2004-10-22
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Abstract

Abstract Contact lenses are both cleaned and disinfected in aqueous solutions of proteolytic enzyme in a single-step by heating to a temperature of between 60 and 100°C. The cleaning and disinfecting process which may be conducted in one hour or less performs favorably against conventional methods wherein cleaning and disinfecting are conducted separately over a time period of up to twelve hours.

Inventors

  • 👤 Lai Ogunbiyi
  • 👤 Thomas Martin Riedhammer
  • 👤 Francis Xavier Smith

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-28 22:04
CPC Classifications
C; C11; C11D; C11D3/00; C11D3/0005; C11D3/0078; A; A61; A61L; A61L12/00; A61L12/02; A61L12/04; C11D3/16; C11D3/38; C11D3/386; C11D3/38609

Claims Analysis

Total Claims: 19
Claim 1
Independent Claim 52 words
In a method of cleaning contact lenses by sequential soaking in an aqueous solution comprising a proteolytic enzyme followed by disinfecting the lenses, the improvement comprising heating the lenses in the aqueous enzyme solution to a temperature sufficient to clean and disinfect the lenses in a single step in the same solution.
Claim 2
Dependent Claim 52 words
In a method of cleaning contact lenses by sequential soaking in an aqueous solution comprising a proteolytic enzyme followed by disinfecting the lenses, the improvement comprising heating the lenses in the aqueous enzyme solution to a temperature sufficient to clean and disinfect the lenses in a single step in the same solution.
Claim 3
Dependent Claim 22 words
The method of claim 1 wherein the heating step is a cycle consisting of a heating phase followed by a cooling phase.
Claim 4
Dependent Claim 20 words
The method of claim 1 wherein the cleaning and disinfection of the lenses is completed in 60 minutes or less.
Claim 5
Dependent Claim 20 words
The method of claim 2 wherein the maximum temperature of,the enzyme solution during the heating phase is less than 100°C.
Claim 6
Dependent Claim 22 words
The method of claim 2 wherein the enzyme solution is heated to a maximum temperature of between about 60° and about 100°C.
Claim 7
Dependent Claim 11 words
The method of claim 1 wherein the enzyme solution contains papain.
Claim 8
Dependent Claim 11 words
The method of claim 1 wherein the enzyme solution contains pancreatin.
Claim 9
Dependent Claim 59 words
In a method of cleaning soft contact lenses by sequential soaking in an aqueous solution comprising a protease followed by disinfecting the lenses, the improvement comprising heating the lenses in the aqueous protease-containing solution to a temperature below 85°C to clean and disinfect the lenses in a single step, said cleaning and disinfecting being conducted in the same solution.
Claim 10
Dependent Claim 59 words
In a method of cleaning soft contact lenses by sequential soaking in an aqueous solution comprising a protease followed by disinfecting the lenses, the improvement comprising heating the lenses in the aqueous protease-containing solution to a temperature below 85°C to clean and disinfect the lenses in a single step, said cleaning and disinfecting being conducted in the same solution.
Claim 11
Dependent Claim 20 words
The method of claim 8 wherein the protease-containing solution includes amylase and the solution is substantially isotonic with lacrimal fluids.
Claim 12
Dependent Claim 22 words
The method of claim 8 wherein the contact lenses are extended-wear type having a water content of at least 55% by weight.
Claim 13
Dependent Claim 19 words
The method of claim 10 wherein the solution is heated to a temperature of about 65 to about 75°C.
Claim 14
Dependent Claim 52 words
In a method of cleaning contact lenses by sequential soaking in an aqueous protease-containing solution followed by disinfecting the lenses, the improvement comprising heating the lenses in an aqueous solution of a microbial protease to a temperature sufficient to clean and disinfect the lenses in a single step in the same solution.
Claim 15
Dependent Claim 52 words
In a method of cleaning contact lenses by sequential soaking in an aqueous protease-containing solution followed by disinfecting the lenses, the improvement comprising heating the lenses in an aqueous solution of a microbial protease to a temperature sufficient to clean and disinfect the lenses in a single step in the same solution.
Claim 16
Dependent Claim 13 words
The method of claim 12 wherein the aqueous solution includes a microbial amylase.
Claim 17
Dependent Claim 22 words
The method of claim 13 wherein the temperature of the aqueous solution is raised to a maximum of between 60 and 100°C.
Claim 18
Dependent Claim 20 words
The method of claim 14 wherein the protease is derived from a Bacillus or Streptomyces bacteria or a Aspergillus mold.
Claim 19
Dependent Claim 13 words
The method of claim 15 wherein the protease is derived from B. subtilis.

References Cited (Backward Citations)

EP0005131A2 Cited
US4327203A Cited
US4690773A Cited

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