A class of pesticides comprising 1,4-bis-substituted-2,6,7-trioxabicyclo(2.2.2)octanes

Claim 2

A compound R-C(CH 2 0) 3 C-X wherein R and X are each organic substituents, the compound exhibiting an LD 50 for pesticidal activity, in micrograms of compound per gram of body weight of Musca domestica of no more than about 400.

Claim 3

A compound as defined in claim 1 in admixture with a synergist, the combination exhibiting an LD 50 for pesticidal activity against Musca domestica of no more than about 60 micrograms per aram.

Claim 4

A compound R-C(CH 2 O) 3 C-X wherein R is propyl, butyl, C 3-10 cycloalkyl or phenyl and X is C 6-10 cycloalkyl, C 6-10 cycloalkenyl, alkynyl or substituted phenyl, as hereinbefore defined, provided that R is not phenyl when X is 4-fluorophenyl.

Claim 5

A compound R-C(CH 2 O) 3 C-X wherein R is propyl, butyl, C 3-10 cycloalkyl or phenyl and X is C 6-10 cycloalkyl, C 6-10 cycloalkenyl, alkynyl or substituted phenyl, as hereinbefore defined, provided that R is not phenyl when X is 4-fluorophenyl.

Claim 6

A compound according to claim 3 wherein R is propyl, butyl, C 5-6 cycloalkyl or phenyl and X is cyclohexyl, cycloheptyl, cyclohexenyl, ethynyl or phenyl substituted by halo, cyano, azido, nitro or C l-2 alkyl, the said C l-2 alkyl being substituted by 1 to 3 halogen atoms, provided that R is not phenyl when X is 4-fluorophenyl.

Claim 7

A compound according to either claim 3 or 4 wherein R is n-propyl, butyl, cyclopentyl or cyclohexyl and X is cyclohexyl, cycloheptyl, or phenyl substituted in the 3- and/or 4- position by substituents independently selected from halo, cyano, azido and nitro.

Claim 8

A compound according to either claim 3 or 4 wherein R is phenyl and X is phenyl substituted in the 3- and/or 4- positions by a substituent independently selected from chloro and bromo.

Claim 9

A compound selected from the group consisting of l-(4-chlorophenyl)-4-n-propyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-n-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-s-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-chlorophenyl)-4-t-butyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-cyclopentyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-chlorophenyl)-4-phenyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-cyclohexyl-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cycloheptyl-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-fluorophenyl}-4-t-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-bromophenyl)-4-t-butyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-nitrophenyl)-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-cyanophenyl)-4-t-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(3,4-dichlorophenyl)-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cyclohexyl-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cycloheptyl-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane,'1-(4-fluorophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-bromophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-cyanophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, and 1-(3,4-dichlorophenyl)-4-cyclohexyl-2,6,7- trioxabicyclo[2.2.2]octane.

Claim 10

A compound selected from the group consisting of l-(4-chlorophenyl)-4-n-propyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-n-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-s-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-chlorophenyl)-4-t-butyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-cyclopentyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-chlorophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-chlorophenyl)-4-phenyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-cyclohexyl-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cycloheptyl-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-fluorophenyl}-4-t-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-bromophenyl)-4-t-butyl-2,6,7- trioxabicyclo[2.2.2]octane, 1-(4-nitrophenyl)-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-cyanophenyl)-4-t-butyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(3,4-dichlorophenyl)-4-t-butyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cyclohexyl-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-cycloheptyl-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane,'1-(4-fluorophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, 1-(4-bromophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo-[2.2.2]octane, 1-(4-cyanophenyl)-4-cyclohexyl-2,6,7-trioxabicyclo[2.2.2]octane, and 1-(3,4-dichlorophenyl)-4-cyclohexyl-2,6,7- trioxabicyclo[2.2.2]octane.

Claim 11

A pesticidal composition comprising a compound according to any of claims 1 to 4 and 7 in admixture with an inert carrier.

Claim 12

A pesticidal composition according to claim 8 which further comprises a synergist as hereinbefore defined.

Claim 13

A compound as defined in any of claims 1 to 4 and 7 for the control of pests.

Claim 15

A method of controlling insects according to claim 11 wherein said pests or their environment are also contacted with a synergist as hereinbefore defined.