EP0183365A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Vascular graft
Assignee: Vascutek Ltd
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Filing: 1985-10-10
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Granted: —
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Expires: 2005-10-10
Abstract
Abstract A method of producing a vascular graft comprises impregnating a tube of flexible porous material with gelatinous material which contains a gelatin which has been treated to cause it to contain a predetermined number of amino groups less than that normally present in untreated gelatin then treating the impregnated tube to cause the amino groups to form cross links with one another. The method provides a vascular graft for use in implantation surgery in which the rate of increase of porosity of the graft after implantation can be accurately determined in advance.
Inventors
- 👤 Roshan Maini
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 06:05
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/50; A61L27/56; A61F; A61F2/00; A61F2/02; A61F2/04; A61F2/06; A61L27/28; A61L27/34; A61L27/507; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/921
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
73 words
A method of producing a vascular graft by impregnating a tube of flexible porous material with gelatinous material then treating the impregnated tube to cause only the amino groups always present in the molecules of gelatinous material to form cross links characterized by including in the gelatinous material a gelatin which has been treated to cause it to contain a predetermined number of amino groups less than that normally present in untreated gelatin.
Claim 2
Independent Claim
73 words
A method of producing a vascular graft by impregnating a tube of flexible porous material with gelatinous material then treating the impregnated tube to cause only the amino groups always present in the molecules of gelatinous material to form cross links characterized by including in the gelatinous material a gelatin which has been treated to cause it to contain a predetermined number of amino groups less than that normally present in untreated gelatin.
Claim 3
Dependent Claim
50 words
A method of producing a vascular graft according to claim 1 characterized in that the gelatinous material comprises a mixture of gelatin treated to contain the predetermined number of amino groups and untreated gelatin, the two gelatins being present in the mixture in a predetermined proportion one to the other.
Claim 4
Dependent Claim
33 words
A method of producing a vascular graft according to claim 1 characterized in that the treated gelatin is treated by reacting it with the anhydride or the chloride of a poiycar- boxylic acid.
Claim 5
Dependent Claim
23 words
4 : A method of producing a vascular graft according to claim 3 characterized in that the polycarboxylic acid is succinic acid COOHCH,CH,COOH.
Claim 6
Dependent Claim
44 words
A method of producing a vascular graft according to claim 1 characterized in that the gelatinous material contains a gelatin which has been previously treated to cause 75% of the amino groups originally in the gelatin before treatment to be converted to carboxyl groups.
Claim 7
Dependent Claim
33 words
A method of producing a vascular graft according to claim 1 characterized by treating the gelatinous material with at least one aldehyde to cause the formation of cross links in the amino groups.
Claim 8
Dependent Claim
37 words
A method of producing a vascular graft according to claim 6 characterized in that the cross linking treatment is a two part treatment in which the impregnated graft is treated first with formaldehyde and then with gluteraldehyde.
Claim 9
Dependent Claim
71 words
A vascular graft produced by impregnating a tube of flexible porous material with gelatinous material then treating the impregnated tube to cause only the amino groups always present in the molecules of gelatinous material to form cross links characterized in that the gelatinous material includes a gelatin which has been previously treated to cause it to contain a predetermined number of amino groups less than that normally present in untreated gelatin.
Claim 10
Dependent Claim
71 words
A vascular graft produced by impregnating a tube of flexible porous material with gelatinous material then treating the impregnated tube to cause only the amino groups always present in the molecules of gelatinous material to form cross links characterized in that the gelatinous material includes a gelatin which has been previously treated to cause it to contain a predetermined number of amino groups less than that normally present in untreated gelatin.
References Cited (Backward Citations)
No citation records indexed.
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