EP0216577A2
Expired / Lapsed
EP
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Sensor
Assignee: Imperial Chemical Industries Ltd
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Filing: 1986-09-11
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Granted: —
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Expires: 2006-09-11
Abstract
Abstract A sensor of the enzyme-electrode type containing a layer of porous material of restricted permeability between the enzyme and a sample to be analysed. The porous material has a percentage porosity not greater than 5% and preferably in the range 0.005% to 0.5%.
Inventors
- 👤 Pankaj Maganlal Vadgama
- 👤 Stephen Dr Churchouse
- 👤 William Mullen
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-11-06 17:24
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/001; C12Q1/002; Y; Y10; Y10S; Y10S435/00; Y10S435/817
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
109 words
A sensor of the enzyme-electrode type for the determination of an analyte, said analyte being convertable in the presence of an enzyme into a species which can be detected by the sensor, which comprises an electrode and a membrane permeable to liquids and solutes positioned between the electrode and a specimen containing the analyte, said membrane comprising a layer containing one or more enzymes and a layer of material positioned between the enzyme-containing layer and the specimen characterised in that said layer of material contains an area through which analyte can pass formed from a porous material of restricted permeability having a porosity which is not greater than 5%.
Claim 2
Dependent Claim
109 words
A sensor of the enzyme-electrode type for the determination of an analyte, said analyte being convertable in the presence of an enzyme into a species which can be detected by the sensor, which comprises an electrode and a membrane permeable to liquids and solutes positioned between the electrode and a specimen containing the analyte, said membrane comprising a layer containing one or more enzymes and a layer of material positioned between the enzyme-containing layer and the specimen characterised in that said layer of material contains an area through which analyte can pass formed from a porous material of restricted permeability having a porosity which is not greater than 5%.
Claim 3
Dependent Claim
42 words
A sensor according to claim 1 which incorporates a laminated membrane comprising an enzyme-containing layer situated between a first layer of material and a second layer of material, the first layer being between the enzyme-containing layer and an electrode in the sensor.
Claim 4
Dependent Claim
22 words
A sensor according to claim 2 wherein the first layer of the membrane is formed from polymethyl methacrylate, cellulose acetate or polyurethane.
Claim 5
Dependent Claim
27 words
A sensor according to any one of claims 1 to 3 wherein the porous material of restricted permeability is formed from a polycarbonate or a modified cellulose.
Claim 6
Dependent Claim
28 words
A sensor according to any one of claims 1 to 4 wherein the porous material of restricted permeability forms the total effective area of the layer containing it.
Claim 7
Dependent Claim
27 words
A sensor according to any one of claims 1 to 5 wherein the porous material of restricted permeability has pores of mean diameter less than 0.03 microns.
Claim 8
Dependent Claim
20 words
A sensor according to claim 6 wherein the pores have a mean diameter in the range 0.01 to 0.03 microns.
Claim 9
Dependent Claim
25 words
A sensor according to any one of claims 1 to 7 wherein the porous material of restricted permeability has a porosity not greater than 2X.
Claim 10
Dependent Claim
16 words
A sensor according to claim 8 wherein the porosity is in the range 0.005% to 0.5%.
Claim 11
Independent Claim
103 words
A method for determining an analyte in a specimen with the outer layer of a membrane, permeable to liquids and solutes and comprising one or more enzymes, in the presence of which the analyte is convertable into a species detectable by a sensor which incorporates the membrane, and one or more layers of material, and measuring the response of the sensor to the species, characterised in that a layer in the membrane between the enzyme and the specimen contains an area through which analyte can pass formed from a porous material of restricted permeability having a porosity which is not greater than 5X.
Claim 12
Independent Claim
103 words
A method for determining an analyte in a specimen with the outer layer of a membrane, permeable to liquids and solutes and comprising one or more enzymes, in the presence of which the analyte is convertable into a species detectable by a sensor which incorporates the membrane, and one or more layers of material, and measuring the response of the sensor to the species, characterised in that a layer in the membrane between the enzyme and the specimen contains an area through which analyte can pass formed from a porous material of restricted permeability having a porosity which is not greater than 5X.
References Cited (Backward Citations)
No citation records indexed.
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