EP0260098A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Magnetic material-physiologically active substance conjugate
Assignee: Bellex Corp
•
Filing: 1987-09-07
•
Granted: —
•
Expires: 2007-09-07
Abstract
Abstract Disclosed is a conjugate comprising a magnetic material and a physiologically active substance bound to each other through a polyethylene glycol derivative, and a conjugate comprising a magnetic material and a polyethylene glycol derivative bound to each other. According to the present invention, a bioreactor enabling application to or recovery of physiologically active substances under liquid state by utilizing the magnetic properties is provided.
Inventors
- 👤 Yuji 1-808 Tamagawa Haimu Inada
- 👤 Yutaka Tamaura
- 👤 Katsunobu Takahashi
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-31 00:36
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/543; G01N33/54353; C; C12; C12N; C12N11/00; C12N11/02; C12N11/08; C12N11/089; C12N11/14; C12N9/00; C12N9/14; C12N9/78; C12N9/80; C12N9/82; C12P; C12P1/00; G01N33/54313; G01N33/54326; G01N33/5434; G01N2446/00; G01N2446/20; G01N2446/30; G01N2446/80; G01N2446/86
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
20 words
A conjugate, comprising a magnetic material and a physiologically active substance bound to each other through a polyethylene glycol derivative.
Claim 2
Dependent Claim
20 words
A conjugate, comprising a magnetic material and a physiologically active substance bound to each other through a polyethylene glycol derivative.
Claim 3
Dependent Claim
15 words
The conjugate, comprising a magnetic material and a polyethylene glycol derivative bound to each other.
Claim 4
Dependent Claim
15 words
The conjugate, comprising a magnetic material and a polyethylene glycol derivative bound to each other.
Claim 5
Dependent Claim
22 words
The conjugate according to Claim 1 or Claim 2, wherein the polyethylene glycol derivative has a molecular weight of 500 to 200,000.
Claim 6
Dependent Claim
40 words
The conjugate according to Claim 1 or Claim 2, wherein the polyethylene glycol derivative has at least one selected from the group consisting of hydroxyl group, carboxyl group, methoxycarbonyl group, amide group, amino group and methoxy group at terminal ends.
Claim 7
Dependent Claim
23 words
The conjugate according to Claim 1 or Claim 2, wherein the polyethylene glycol derivative has carboxyl group or methoxycarbonyl group at terminal ends.
Claim 8
Dependent Claim
30 words
The conjugate according to Claim 1 or Claim 2, wherein the magnetic material is a transition metal or its ion, its oxide or a compound of these with other elements.
Claim 9
Dependent Claim
21 words
The conjugate according to Claim 1 or Claim 2, wherein the magnetic material is formed from ferrous chloride or ferric chloride.
Claim 10
Dependent Claim
17 words
The conjugate according to Claim 1 or Claim 2, wherein the magnetic material is ferrite or magnetite.
Claim 11
Dependent Claim
19 words
The conjugate according to Claim 1 or Claim 2, wherein the magnetic material is erbium oxide or dysprosium chloride.
Claim 12
Dependent Claim
70 words
The conjugate according to Claim 1, wherein the physiologically active substance is an enzyme, a protein, an antibody, an antigen, a polysaccharide, a nucleic acid, a lipid, an amino acid, a co-enzyme, a high energy phosphoric acid compound, a prosthetic group, a hormone, a vitamin, a receptor, a ligand, an antibiotic, an antitumor substance or a pharmaceutical, or a chloroplast, a mitochrondrion, a virus, a cell or a constituent thereof.
Claim 13
Dependent Claim
21 words
The conjugate according to Claim 1, wherein the physiologically active substance is an enzyme, a protein, an antibody or an antigen.
Claim 14
Dependent Claim
14 words
The conjugate according to Claim 1, wherein the physiologically active substance is an enzyme.
Claim 15
Dependent Claim
13 words
The conjugate according to Claim 1, wherein the physiologically active substance is lipase.
Claim 16
Dependent Claim
39 words
The conjugate according to Claim 2, wherein the physiologically active substance is α,ω-di-carboxy polyethylene glycol or α,ω-dimethoxycarbonyl polyethylene glycol having a molecular weight of 500 to 200,000 and the magnetic material is formed from ferrous chloride and ferric chloride.
Claim 17
Dependent Claim
14 words
The conjugate according to Claim 14, wherein an enzyme is bound to the conjugate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.