EP0321403A2
Expired / Lapsed
EP
⏱️ 0.0 years remaining
Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bond through ether groups and hydrogel contact lenses made therefrom
Assignee: BASF Schweiz AG
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Filing: 1988-12-07
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Granted: —
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Expires: 2008-12-07
Abstract
Abstract A contact lens of a crosslinked, organic aprotic solvent insoluble, substantially transparent polymer of a derivative of a polyvinyl alcohol having a weight average molecular weight of at least about 2,000, containing an effective amount between about 0.1 and 90 percent, based on the number of hydroxyl groups on said polyvinyl alcohol, of a crosslinked addition reaction product of units of the formula in the presence or absence of a polymerizable vinylic monomer wherein R 1 is a divalent aliphatic, cycloaliphatic, aryl, aralkyl or alkaryl group; A is -O-, -NH- or -NHCON(R")- where R" is hydrogen or lower alkyl and A' is a direct bond; or A is a direct bond and A' is -O-or -0-CH 2 -; R 2 is hydrogen or methyl; and R is hydrogen, methyl or -COOR 4 where R 4 is hydrogen or lower alkyl; with the proviso that if R 2 is methyl, R 3 is hydrogen; and wherein the polymerizable vinylic monomer, if present, is hydrophobic or is a mixture of hydrophobic and hydrophilic vinylic monomers in which mixture at least 50 % of vinyl monomers are hydrophobic.
Inventors
- 👤 Merrill Goldenberg
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-24 16:28
CPC Classifications
G; G02; G02B; G02B1/00; G02B1/04; G02B1/041; G02B1/043; C; C08; C08F; C08F290/00; C08F290/08; C08F290/12
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
186 words
A contact lens of a crosslinked, organic aprotic solvent insoluble, substantially transparent polymer of a derivative of a polyvinyl alcohol having a weight average molecular weight of at least about 2,000, containing an effective amount between about 0.1 and 90 percent, based on the number of hydroxyl groups on said polyvinyl alcohol, of a crosslinked addition reaction product of units of the formula in the presence or absence of a polymerizable vinylic monomer wherein R is a divalent aliphatic, cycloaliphatic, aryl, aralkyl or alkaryl group; A is -O - , -NH- or -NHCON(R")- where R" is hydrogen or lower alkyl and A' is a direct bond; or A is a direct bond and A' is -O-or -O-CH 2 -; R 2 is hydrogen or methyl; and R 3 is hydrogen, methyl or -COOR 4 where R 4 is hydrogen or lower alkyl; with the proviso that if R 2 is methyl, R 3 is hydrogen; and wherein the polymerizable vinylic monomer, if present, is hydrophobic-or is a mixture of hydrophobic and hydrophilic vinylic monomers in which mixture at least 50 % of vinyl monomers are hydrophobic.
Claim 2
Dependent Claim
186 words
A contact lens of a crosslinked, organic aprotic solvent insoluble, substantially transparent polymer of a derivative of a polyvinyl alcohol having a weight average molecular weight of at least about 2,000, containing an effective amount between about 0.1 and 90 percent, based on the number of hydroxyl groups on said polyvinyl alcohol, of a crosslinked addition reaction product of units of the formula in the presence or absence of a polymerizable vinylic monomer wherein R is a divalent aliphatic, cycloaliphatic, aryl, aralkyl or alkaryl group; A is -O - , -NH- or -NHCON(R")- where R" is hydrogen or lower alkyl and A' is a direct bond; or A is a direct bond and A' is -O-or -O-CH 2 -; R 2 is hydrogen or methyl; and R 3 is hydrogen, methyl or -COOR 4 where R 4 is hydrogen or lower alkyl; with the proviso that if R 2 is methyl, R 3 is hydrogen; and wherein the polymerizable vinylic monomer, if present, is hydrophobic-or is a mixture of hydrophobic and hydrophilic vinylic monomers in which mixture at least 50 % of vinyl monomers are hydrophobic.
Claim 3
Dependent Claim
16 words
A contact lens according to claim 1 which is substantially devoid of said polymerizable vinylic monomer.
Claim 4
Dependent Claim
27 words
A contact lens according to claim 1 wherein said polymer contains between about 0.01 and about 80 units of polymerizable hydrophobic monomer, per unit of formula I.
Claim 5
Dependent Claim
49 words
A contact lens according to claim 1 wherein said polymer contains between about 0.01 and about 80 units of polymerizable monomer, per unit of formula I, said monomer being a mixture of hydrophobic and hydrophilic vinylic monomers in which mixture at least 50 % of vinyl monomers are hydrophobic.
Claim 6
Dependent Claim
129 words
A contact lens according to claim 1 wherein R 1 is straight or branched chain alkylene of 1 to 20 carbon atoms, or straight or branched chain alkylene of 2 to about 100 carbon atoms interrupted by one or more hetero atoms or hetero atom containing groups selected from carbonyloxy, oxycarbonylamido, sulfonamido, carbonamido, sulfonyl, sulfoxy, or oxy, and R 1 is further unsubstituted or substituted by hydroxy, or R 1 is phenylene which is unsubstituted or substituted by lower alkyl or lower alkoxy, cyclohexylene or cyclohexylene lower alkylene, which is unsubstituted or substituted by one or more methyl groups in the cyclohexylene moiety, phenylenealkylene or alkylenephenylene which is unsubstituted or substituted by lower alkyl or lower alkoxy in the phenylene moiety and the alkylene moiety thereof is lower alkylene.
Claim 7
Dependent Claim
59 words
A contact lens according to claim 1, wherein R 1 is straight or branched chain alkylene of 1 to 20 carbon atoms, or straight or branched chain alkylene of 2 to about 100 carbon atoms interrupted by one or more of carbonyloxy, oxycarbonylamido, sulfonamido, carbonamido, sulfonyl, sulfoxy, or oxy, and R 1 is further unsubstituted or substituted by hydroxy.
Claim 8
Dependent Claim
27 words
A contact lens according to claim 6 wherein said polymer contains between about 0.01 and about 80 units of polymerizable hydrophobic monomer, per unit of formula I.
Claim 9
Dependent Claim
17 words
A contact lens according to claim 7 wherein the polymerizable hydrophobic monomer is a lower alkyl methacrylate.
Claim 10
Dependent Claim
35 words
A contact lens according to claim 1 wherein R 1 is lower alkylene or lower alkylene interrupted by one group selected from carbonyloxy, carbonamido and oxycarbonylamido, A is -O- and A' is a direct bond.
Claim 11
Dependent Claim
27 words
A contact lens according to claim 9 wherein said polymer contains between about 0.01 and about 80 units of polymerizable hydrophobic monomer, per unit of formula I.
Claim 12
Dependent Claim
17 words
A contact lens according to claim 10 wherein the polymerizable hydrophobic monomer is a lower alkyl methacrylate.
Claim 13
Dependent Claim
24 words
A contact lens according to claim 5 wherein R is alkylene of 2 to 10 carbon atoms and is unsubstituted or substituted by hydroxy.
Claim 14
Dependent Claim
27 words
A contact lens according to claim 12 wherein said polymer contains between about 0.01 and about 80 units of polymerizable hydrophobic monomer, per unit of formula I.
Claim 15
Dependent Claim
17 words
A contact lens according to claim 13 wherein the polymerizable hydrophobic monomer is a lower alkyl methacrylate.
Claim 16
Dependent Claim
21 words
A contact lens according to claim 1, wherein the polyvinyl alcohol has a weight average molecular weight of at least 10,000.
Claim 17
Dependent Claim
36 words
A contact lens according to claim 1, in which the polyvinyl alcohol derivative contains between about 0.1 and about 20 percent units of formula I, based on the number of hydroxyl groups of said polyvinyl alcohol.
Claim 18
Dependent Claim
51 words
A contact lens according to claim 16, in which said units of formula I are reacted with 0.01 to 80 units of a vinylic polymerizable monomer which is hydrophobic or a mixture of hydrophobic and hydrophilic monomers containing at least 50 weight percent of hydrophobic monomer, based upon total monomer reactant.
Claim 19
Dependent Claim
31 words
A process for the manufacture of a contact lens according to claim 1 which is conventional per se and is characterized in that a polymer according to claim 1 is used.
Claim 20
Dependent Claim
19 words
Use of a polymer according to claim 1 for the manufacture of a contact lens according to claim 1.
References Cited (Backward Citations)
No citation records indexed.
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