EP0711991A1 Expired / Lapsed EP ⏱️ 0.0 years remaining

Particle analyzer

Assignee: Sysmex Corp

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Filing: 1995-11-14

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Granted: —

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Expires: 2015-11-14

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Abstract

Abstract A particle analyzer includes a flow cell (5) including a first and second cells (7a,7b) for containing electrolyte with particle floating therein, the first and second cells (7a,7b) being connected to each other by a pore (11) to allow the particles to flow from the first cell (7a) to the second cell (7b) through the pore (11) ; a first and second eletrodes (12,13) provided in the electrolyte in the first and second cells respectively ; a first detector for detecting an electric resistance between the first and second electrodes which changes according as the particle passes through the pore to generate an electric resistance signal representative of the electric resistance ; a light source for emitting a beam of light to the flowing particle ; a second detector for detecting scattered light from the particle receiving the beam of light to generate a scattered light signal representative of an intensity of the scattered light ; a clock device for clocking a period of time during which the scattered light signal is generated ; and an analyzer for classifying the particle based on a correlation between the electric resistance signal and the clocked period of time.

Inventors

👤 Masakazu Fukuda
👤 Masaaki Oka
👤 Hiroyuki Nakamoto

Bibliographic Details

Application Number —

Jurisdiction EP

Data Source google_patents

Last Synchronized 2026-11-06 07:28

CPC Classifications

G; G01; G01N; G01N15/00; G01N15/10; G01N15/14; G01N15/1456; G01N2015/1019

Claims Analysis

Total Claims: 5

Claim 1

Independent Claim 199 words

A particle analyzer comprising : a flow cell (5) including a first and second cells (7a,7b) for containing electrolyte, the first and second cells being connected to each other by a pore (11) to allow particles to flow from the first cell (7a) to the second cell (7b) through the pore (11) ; a first and second electrodes (12,13) provided in the electrolyte in the first and second cells (7a,7b) respectively ; first detecting means (16) for detecting an electric resistance between the first and second electrodes which changes according as the particle passes through the pore (11) to generate an electric resistance signal (29) representative of the electric resistance ; a light source (17) for emitting a beam of light to the flowing particle ; second detecting means (25) for detecting scattered light from the particle receiving the beam of light to generate a scattered light signal (28) representative of an intensity of the scattered light ; clock means (52) for clocking a period of time during which the scattered light signal is generated ; and analysis means (47) for classifying the particle based on a correlation between the electric resistance signal and the clocked period of time.

Claim 2

Dependent Claim 110 words

A particle analyzer according to claim 1, further comprising ; comparison means (36,37) for comparing the scattered light signal (28) obtained by the second detecting means (25) with a first reference value as well as a second reference value larger than the first reference value ; second clock means (41,42) for clocking a first period of time during which the scattered light signal is larger than the first reference value and a second period of time during which the scattered light signal is larger than the second reference value ; and second analysis means for classifying the particle based on a correlation between the first and second periods of time.

Claim 3

Dependent Claim 109 words

A particle analyzer according to claim 1, further comprising : third detecting means (24) for detecting fluorescence from the particle receiving the beam of light to generate a fluorescence signal (27) representative of an intensity of the fluorescence ; second comparison means (39) for comparing the fluorescence signal means with a third reference value ; third clock means (44) for clocking a third period of time during which the fluorescence signal (27) is larger than the third reference value ; and third analysis means for classifying the particle based on a correlation between the clocked third period of time and the scattered light signal (28) generated period of time.

Claim 4

Dependent Claim 47 words

A particle analyzer according to claim 2, further comprising ; peak detecting means (38) for detecting a maximum value of the scattered light signal (28) obtained by the second detecing means (25) ; and fourth analysis means for classifying the particle based on the obtained maximum value.

Claim 5

Dependent Claim 44 words

A particle analyzer according to claim 3, further comprising : peak detecting means (50) for detecting a maximum value of the fluorescence signal obtained by the third detecting means (24) ; fifth analysis means for classifying the particle based on the obtained maximum value.

References Cited (Backward Citations)

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US4298836A Cited

EP0121261A2 Cited

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JPH01250037A Cited

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