US2862851A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Aldosterone, process for preparation and compositions thereof
Assignee: Individual
•
Filing: 1954-07-20
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Granted: 1958-12-02
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Expires: 1974-07-20
Abstract
No abstract record available.
Inventors
- 👤 Reichstein Tadeus
- 👤 Wettstein Albert
- 👤 Neher Robert
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 22:16
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/56; A61K31/57; A61K31/573
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
101 words
THE PROCESS FOR ISOLATION FROM SUPRARNAL GLANDS OF BIOLOGICALLY ACTIVE, CHEMICALLY UNITARY, CRYSTALLINE PRODUCT OF MANUFACTURE, ALDOSTERONE, WHICH COMPRISES THE STEPS OF SEPERATING BY PARTITION CHROMATOGRAPHY ON KIESELGUHR BETWEEN WATER, AND BENZENE AND PETROLEUM ETHER, AN EXTRACT OBTAINED FROM SUPRARENAL GLANDS WITH LIPOID SOLVENTS, COLLECTING THE ELUATES OBTAINED WITH BENZENEPETROLEUM ETHER IN THE RATIO FROM 63:35 TO 90:10, EVAPORATING THE SOLVENTS, SEPARATING THE RESIDUE BY A SECOND CHROMATOGRAPHY ON CELLULOSE BETWEEN WATER-METHANOL (4:6) AND TOLUENE-PETROLEUM ETHER, COLLECTING THE ELUATES OBTAINED WITH TOLUENE-PETROLEUM ETHER IN THE RATIO 3:1 EVAPORATING THE SOLVENTS, AND CRYSTALLIZING THE RESIDUE FROM ACETONE-ETHER WHEREBY ARYSTALLINE ALDOSTERONE IS OBTAINED.
Claim 2
Dependent Claim
101 words
THE PROCESS FOR ISOLATION FROM SUPRARNAL GLANDS OF BIOLOGICALLY ACTIVE, CHEMICALLY UNITARY, CRYSTALLINE PRODUCT OF MANUFACTURE, ALDOSTERONE, WHICH COMPRISES THE STEPS OF SEPERATING BY PARTITION CHROMATOGRAPHY ON KIESELGUHR BETWEEN WATER, AND BENZENE AND PETROLEUM ETHER, AN EXTRACT OBTAINED FROM SUPRARENAL GLANDS WITH LIPOID SOLVENTS, COLLECTING THE ELUATES OBTAINED WITH BENZENEPETROLEUM ETHER IN THE RATIO FROM 63:35 TO 90:10, EVAPORATING THE SOLVENTS, SEPARATING THE RESIDUE BY A SECOND CHROMATOGRAPHY ON CELLULOSE BETWEEN WATER-METHANOL (4:6) AND TOLUENE-PETROLEUM ETHER, COLLECTING THE ELUATES OBTAINED WITH TOLUENE-PETROLEUM ETHER IN THE RATIO 3:1 EVAPORATING THE SOLVENTS, AND CRYSTALLIZING THE RESIDUE FROM ACETONE-ETHER WHEREBY ARYSTALLINE ALDOSTERONE IS OBTAINED.
Claim 3
Dependent Claim
6 words
A CRYSTALLINE PRODUCT OF MANUFACTURE, ALDOSTERONE.
Claim 4
Dependent Claim
6 words
A CRYSTALLINE PRODUCT OF MANUFACTURE, ALDOSTERONE.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1961-12-01 | 1962-06-02 | 1962-12-02 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1965-12-01 | 1966-06-02 | 1966-12-02 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1969-12-01 | 1970-06-02 | 1970-12-02 | $7700.00 | Window Closed / Lapsed |