US2894007A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for preparing 9alpha-fluoro steroids
Assignee: Merck and Co Inc
•
Filing: 1955-02-03
•
Granted: 1959-07-07
•
Expires: 1975-02-03
Abstract
No abstract record available.
Inventors
- 👤 Robert P Graber
- 👤 Jr C Stewart Snoddy
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 06:55
CPC Classifications
C; C07; C07J; C07J5/00; C07J75/00
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
61 words
IN THE PROCESS WHEREIN HYDROGEN FLOURIDE IS REACTED WITH A 9B, 11B-OXIDE-STERIOD TO PRODUCE THE CORRESPONDING 9A-FLUORO-11BHYDROXY-STEROID, THE IMPROVEMENT WHICH COMPRISES CARRYING OUT THE REACTION IN AN AQUEOUS SOLVENT MEDIUM AND IN THE PRESENCE OF A NON-OXIDIZING ACID SELECTED FROM THE GROUP CONSISTING OF PERCHLORIC ACID, SULFURIC ACID, TRICHLORACETIC ACID, THE LOWER ALKANESULFONIC ACIDS P-NITROBENZENESULFONIC ACID AND 2-4 DINITROB ENZENESULFONIC ACID.
Claim 2
Dependent Claim
61 words
IN THE PROCESS WHEREIN HYDROGEN FLOURIDE IS REACTED WITH A 9B, 11B-OXIDE-STERIOD TO PRODUCE THE CORRESPONDING 9A-FLUORO-11BHYDROXY-STEROID, THE IMPROVEMENT WHICH COMPRISES CARRYING OUT THE REACTION IN AN AQUEOUS SOLVENT MEDIUM AND IN THE PRESENCE OF A NON-OXIDIZING ACID SELECTED FROM THE GROUP CONSISTING OF PERCHLORIC ACID, SULFURIC ACID, TRICHLORACETIC ACID, THE LOWER ALKANESULFONIC ACIDS P-NITROBENZENESULFONIC ACID AND 2-4 DINITROB ENZENESULFONIC ACID.
Claim 3
Dependent Claim
38 words
A PROCESS WHICH COMPRISES REACTING 9B,11B-OXIDO-4PREGENE 17A,21-DIOL-3,20-DIONE 21-ACETATER WITH AQUEOUS HYDROGEN FLUORIDE AT APPROXIMATELY 0* TO 5*C. IN THE PRESENCE OF A MIXTURE OF CHLOROFORM AND PERCHLORIC ACID TO PRODUCE 9AFLUORO-4-PREGENE - 11B, 17A 21- TRIOL- 3,20DIONE 21-ACETATE.
Claim 4
Dependent Claim
38 words
A PROCESS WHICH COMPRISES REACTING 9B,11B-OXIDO-4PREGENE 17A,21-DIOL-3,20-DIONE 21-ACETATER WITH AQUEOUS HYDROGEN FLUORIDE AT APPROXIMATELY 0* TO 5*C. IN THE PRESENCE OF A MIXTURE OF CHLOROFORM AND PERCHLORIC ACID TO PRODUCE 9AFLUORO-4-PREGENE - 11B, 17A 21- TRIOL- 3,20DIONE 21-ACETATE.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1962-07-06 | 1963-01-05 | 1963-07-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1966-07-06 | 1967-01-05 | 1967-07-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1970-07-06 | 1971-01-05 | 1971-07-07 | $7700.00 | Window Closed / Lapsed |