Delta**4,9,11-trienes of the 19-nor-androstene series and process for their manufacture
Abstract
Abstract PROCESS FOR THE MANUFACTURE OF $4,9,11-TRIENES OF THE 19NOR-ANDROSTANE SERIES, IN WHICH 17-OXYGENATED 3-OXO$5(10)9(11)-19-NOR-ANDROSTADIENES ARE TREATED WITH ONE MOL EQUIVALENT OF A PERACID, THE MONOEPOXIDES SO OBTAINED OR MIXTURES THEREOF ARE TREATED WITH A LEWIS ACID, IF DESIRED, AFTER TREATMENT WITH AN ADSORBENT CONTAINING SILICA OR ALUMINA. IF DESIRED, FUNCTIONALLY MODIFIED HYDROXYL GROUPS OR OXO GROUPS THAT ARE PRESENT ARE CONVERTED INTO FREE HYDROXYL OR OXO GROUPS OF FREE HYDROXYL GROUPS ARE FUNCTIONALLY MODIFIED, OR DEHYDROGENATED TO AN OXO GROUP AND/OR A 17-OXO GROUP IS REDUCED, IF DESIRED, WITH SIMULTANEOUS INTRODUCTION OF A HYDROCARBON RADICAL IN 17APOSITION. THE COMPOUNDS OF THE INVENTION DISPLAY EXCEPTIONALLY HIGH ANDROGENIC AND ANABOLIC OR GEATAGENIC ACTIVITY.
Inventors
- 👤 Georg Anner
- 👤 Peter Wieland
Bibliographic Details
Claims Analysis
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1974-04-26 | 1974-10-26 | 1975-04-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1978-04-26 | 1978-10-26 | 1979-04-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1982-04-26 | 1982-10-26 | 1983-04-27 | $7700.00 | Window Closed / Lapsed |