Biologically active substituted-s-triazines
Abstract
Abstract -CO-ALKYL, -COO-Z, -CO-ALK-X-ALKYL, (Y,Y''-PHENYL)-X-ALK-CO-, (Y,Y''-CYCLOHEXYL)-X-ALK-CO- (Y,Y''-NAPHTH-1-YL)-X-ALK-CO-, (Y,Y''-PERHYDRONAPHTH-1- YL)-X-ALK-CO-, IN WHICH X IS O OR S, Z IN ALKYL, PHENYL, NAPHTHYL OR CYCLOHEXYL, ALK IS ALKYLENE AND THE ALKYL AND ALKYLENE INCLUDED IN R, R1 TO R3 AND Z HAVING UP TO 6 CARBON ATOMS AND THEIR PHARMOCOLOGICALLY ACCEPTABLE ACID ADDITION SALTS. 2-((4-R3-PIPERAZIN-1-YL)-),4-R1,6-R2-S-TRIAZINE IN WHICH R1 IS-NRALKY, (Y,Y''-PHENYL)-N(-R)-, (Y,Y''-CYCLOHEXYL)-N(-R)-, SUBSTITUTED-S-TRIAZINES HAVING ANTI-INFLAMMATORY ACTION OF THE FORMULA (Y,Y''-NAPHTH-1-YL)-N(-R)-, (Y,Y''-PERHYDRONAPHTH-1-YL)-N(-R)-, WHEREIN ALKYL IS ALKYL OR ALKYL SUBSTITUTED WITH CN OR CL; R HAS THE SAME SIGNIFICANCE AS ALKYL BUT IN ADDITION CAN BE HYDROGEN; EACH OF Y AND Y'' ARE HYDROGEN, HALOGENS, NO2, -ALKYL, -OALKYL, OH OR COOH; R2 IS MORPHOLINO, PIPERAZINO, PYRROLIDINO, -S-ALKYL, -O-ALKYL OR -C(-CL)3 R3 IS
Inventors
- 👤 Werner Heimberger
- 👤 Hermann Schmitt
Bibliographic Details
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