Cycloalkanecarboxamides
Abstract
Abstract COMPOUNDS OF FORMUALAE XI AND XII (BOTH IN CIS AND TRANS FORMS) (-CH(-N(-R3)-R4)-CH2-(CH2)N-CH2-)>CH-CO-N(-R1)-R2 (XI) (-CH(-N(-R3)-R4)-CH2-(CH2)N-CH2-)>CH-CH2-N(-R1)-R2 (XII) WHEREIN N IS A NUMBER OF 1 TO 3, INCLUSIVE; R1 IS HYDROGEN, ALKYL OF 1 TO 6 CARBON ATOMS, INCLUSIVE, OR CYCLOALKYL OF 5 TO 7 CARBON ATOMS, INCLUSIVE; R2 IS ALKYL OR CYCLOALKYL DEFINED AS ABOVE, OR TOGETHER -N(-R1)-R2 IS A HETEROCYCLIC-AMINO GROUP; AND R3 AND R4 ARE ALKYL OR TOGETHER -N(-R3)-R4 IS A HETEROCYCLIC-AMINO GROUP, ARE PREPARED, THE COMPOUNDS AND THE PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF HAVE VARIOUS PHARMACOLOGICAL ACTIVITIES, E.G., HYPOGLCEMIC, SEDATIVE, AND ANTI-INFLAMMATORY ACTIVITIES AND CAN BE USED IN MAMMALS AND BIRDS TO PRODUCE A LOWERING OF BLOOD SUGAR, TO TRANQUILIZE OR TO REDUCE INFLAMMATORY OR ARTHRITIC CONDITIONS.
Inventors
- 👤 Ronald H Rynbrandt
- 👤 Louis L Skaletzky
Bibliographic Details
Claims Analysis
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