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US3674840A Expired / Lapsed US ⏱️ 0.0 years remaining

1-(para-alkoxyalkoxy-phenyl)-2-hydroxy-3-alkylaminopropanes and the salts thereof

Assignee: Individual
•
Filing: 1970-05-19
•
Granted: 1972-07-04
•
Expires: 1990-05-19
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Abstract

Abstract Compounds of the formula: WHERE Z is an oxaradical (a) R-O-(CH2)n-O-, (b) R-O-(CH2)m-O(CH2)n-O-; n is an integer equal to 2-3; m is an integer equal to 2-3 and R is an alkyl radical having one to five carbon atoms; and pharmaceutically acceptable, non-toxic, acid addition salts thereof. Illustrative are compounds where R is isopropyl or tbutyl and Z is CH3-O-CH2-CH2-O-, or CH3-O-CH2CH2-O-CH2CH2-O-. Also pharmaceutical compositions containing these compounds, and the use thereof in treating cardiovascular diseases.

Inventors

  • 👤 Arne Elof Grandstrom
  • 👤 Per Arvid Emil Carlsson
  • 👤 Stig Ake Ingemar Carlsson
  • 👤 Hans Rudolf Corrodi
  • 👤 Lars Ek
  • 👤 Bo Robert Lamm
  • 👤 Bengt Arne Hjalmar Ablad

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 19:46
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/13; A61K31/135; A61P; A61P9/00; A61P9/06; A61P9/08; C; C07; C07C; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07C59/68; C07D; C07D303/00; C07D303/02; C07D303/12; C07D303/18; C07D303/20; C07D303/24; Y; Y02; Y02P; Y02P20/00; Y02P20/50; Y02P20/55

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 5 words
A compound of the formula:
Claim 2
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents isopropyl and R2 is -CH2CH2OCH3, and pharmaceutically acceptable, non-toxic acid addition salts thereof.
Claim 3
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents isopropyl and R2 is -CH2CH2OC2H5, and pharmaceutically acceptable, non-toxic acid addition salts thereof.
Claim 4
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents isopropyl and R2 is -CH2CH2OCH(CH3)2, and pharmaceutically acceptable, non-toxic acid addition salts thereof.
Claim 5
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents isopropyl and R2 is -CH2CH2OCH2CH2OCH3, and pharmaceutically acceptable, non-toxic acid addition salts thereof.
Claim 6
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents isopropyl and R2 is -CH2CH2CH2OCH3, and pharmaceutically acceptable, non-toxic acid addition salts thereof.
Claim 7
Dependent Claim 22 words
A compound according to claim 2, wherein R1 represents t-butyl and R2 is -CH2CH2CH2OCH3, and pharmaceutically acceptable, non-Toxic acid addition salts thereof.

References Cited (Backward Citations)

US3337628A Cited
US3275629A Cited
US3410901A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1975-07-04 1976-01-03 1976-07-04 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1979-07-04 1980-01-03 1980-07-04 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1983-07-04 1984-01-03 1984-07-04 $7700.00 Window Closed / Lapsed

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