US3678170A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Pharmaceutical method and compositions employing substituted chromanone oximes and chromanone oxime ethers
Assignee: EIDP Inc
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Filing: 1970-03-26
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Granted: 1972-07-18
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Expires: 1990-03-26
Abstract
Abstract This disclosure teaches the preparation of chromanone oximes, such as, 7,8-dichloro-4-chormanone oxime and their use as diuretics in warm-blooded mammals.
Inventors
- 👤 Robert D Irsay
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 08:23
CPC Classifications
C; C07; C07D; C07D311/00; C07D311/02; C07D311/04; C07D311/58
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
68 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of a compound of the formula where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen; and X is bromine or chlorine.
Claim 2
Independent Claim
62 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of a compound of the formula where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine and chlorine, with the limitation that at last one of R1 and R2 must be hydrogen.
Claim 3
Independent Claim
62 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of a compound of the formula where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine, and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen.
Claim 4
Independent Claim
21 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of 7-chloro-6-fluoro-4-chromanone oxime.
Claim 5
Independent Claim
23 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of 7-chloro-6-fluoro-4-chromanone oxime methyl ether.
Claim 6
Independent Claim
21 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of 7-chloro-8-fluoro-4-chromanone oxime.
Claim 7
Independent Claim
23 words
A method of producing a diuretic effect in mammals comprising administering to said mammal a diuretically effective amount of 7-chloro-8-fluoro-4-chromanone oxime methyl ether.
Claim 8
Dependent Claim
83 words
A pharmaceutical composition containing from 1 percent to 99.98 percent by weight of a pharmaceutical carrier in combination with from 0.02 percent to 99 percent by weight of a diuretic compound of the formula where R is hydrogen or methyl; R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen; and X is bromine or chlorine.
Claim 9
Dependent Claim
61 words
The pharmaceutical composition of claim 9 in which the active ingredient is a compound of the formula: where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen; and X is bromine or chlorine.
Claim 10
Dependent Claim
55 words
The pharmaceutical composition of claim 9 in which the active ingredient is a compound of the formula: where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen.
Claim 11
Dependent Claim
55 words
The pharmaceutical composition of claim 9 in which the active ingredient is a compound of the formula: where R1 and R2 can be the same or different and are each selected from the group consisting of hydrogen, bromine, fluorine, and chlorine, with the limitation that at least one of R1 and R2 must be hydrogen.
Claim 12
Dependent Claim
14 words
The pharmaceutical composition of claim 9 in which the active ingredient is 7-chloro-6-fluoro-4-chromanone oxime.
Claim 13
Dependent Claim
16 words
The pharmaceutical composition of claim 9 in which the active ingredient is 7-chloro-6-fluoro-4-chromanone oxime methyl ether.
Claim 14
Dependent Claim
14 words
The pharmaceutical composition of claim 9 in which the active ingredient is 7-chloro-8-fluoro-4-chromanone oxime.
Claim 15
Dependent Claim
16 words
The pharmaceutical composition of claim 9 in which the active ingredient is 7-chloro-8-fluoro-4-chromanone oxime methyl ether.
Claim 16
Dependent Claim
22 words
The unit pharmaceutical dosage form of the composition of claim q selected from the group consisting of a capsule and a tablet.
Claim 17
Dependent Claim
22 words
The unit pharmaceutical dosage form of the composition of claim 9 selected from the group consisting of a syrup and a suspension.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-07-18 | 1976-01-17 | 1976-07-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-07-18 | 1980-01-17 | 1980-07-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-07-18 | 1984-01-17 | 1984-07-18 | $7700.00 | Window Closed / Lapsed |