US3689488A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Certain s-triazolo 1,5-a pyrimidines
Assignee: Imperial Chemical Industries Ltd
•
Filing: 1969-08-14
•
Granted: 1972-09-05
•
Expires: 1989-08-14
Abstract
Abstract A series of novel 5-(or 7-)oxo or thioxo dihydro-s-triazolo(1,5a)pyrimidine derivatives bearing an amino, substituted amino or carboxy derivative in the 2-position, an alkyl or alkenyl substituent in the 4-position and, optionally a halogen or alkyl substituent in the 6-position. These compounds prevent bronchospasm and are therefore useful in the treatment of asthma.
Inventors
- 👤 Michael Dukes
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 22:58
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/04; C07D249/00; C07D249/02; C07D249/08; C07D249/10; C07D249/14
Claims Analysis
Total Claims: 13
Claim 1
Independent Claim
34 words
A triazolo-pyrimidine derivative according to claim 1 wherein X is oxo or thioxo, Y is hydrogen or methyl, and the nucleus contains a double bond between the carbon atoms in positions 6 and 7.
Claim 2
Dependent Claim
15 words
A triazolo-pyrimidine derivative according to claim 2 wherein X is oxo and Y is hydrogen.
Claim 3
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-methyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5-a)pyrimidine.
Claim 4
Dependent Claim
10 words
The triazolo-pyrimidine according to claim 1 which is 2-n-propylamino-6-methyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5 -a)pyrimidine.
Claim 5
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-methyl-4-n-butyl-5-oxo-4,5-dihydro-s-triazolo(1,5-2)pyrimidine.
Claim 6
Dependent Claim
10 words
The triAzolo-pyrimidine according to claim 1 which is 2-isopropylamino-6-methyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5 -a)pyrimidine.
Claim 7
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-methyl-4-allyl-5-oxo-4,5-dihydro-s-triazolo(1,5-a)pyrimidine.
Claim 8
Dependent Claim
10 words
The triazolo-pyrimidine according to claim 1 which is 2-p-chlorobenzamido-6-methyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5 -a)pyrimidine.
Claim 9
Dependent Claim
10 words
The triazolo-pyrimidine according to claim 1 which is 2-ethoxycarbonylamino-6-methyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5 -a)pyrimidine.
Claim 10
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-4,6-di-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5-a)pyrimidine.
Claim 11
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-methyl-4-s-butyl-5-oxo-4,5-dihydro-s-triazolo(1,5-a)pyrimidine.
Claim 12
Dependent Claim
10 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-methyl-4-s-cyclopentyl-5-oxo-4,5-dihydro-s-triazolo(1,5 -a)pyrimidine.
Claim 13
Dependent Claim
9 words
The triazolo-pyrimidine according to claim 1 which is 2-amino-6-n-butyl-4-n-propyl-5-oxo-4,5-dihydro-s-triazolo(1,5-a)pyrimidine.
References Cited (Backward Citations)
US3202512A
Cited
US3271401A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-09-05 | 1976-03-06 | 1976-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-09-05 | 1980-03-06 | 1980-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-09-05 | 1984-03-06 | 1984-09-05 | $7700.00 | Window Closed / Lapsed |