US3689646A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antimutagenic treatment of bacteria
Assignee: University of Pennsylvania
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Filing: 1969-09-04
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Granted: 1972-09-05
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Expires: 1989-09-04
Abstract
Abstract This invention is concerned with a method of killing bacteria with a bactericide so as not to inherently produce bacteria strains resistant to the bactericide. In the method of this invention, the bactericide is utilized along with an effective amount of an antimutagenic agent such as spermine, spermidine, quinacrine hydrochloride, chlorpromazine, promethazine, levomepromazine, cyclobenzaprine, 3-chlorodibenzocycloheptene, protriptyline, amitriptyline, azepine hydrochloride and imipramine.
Inventors
- 👤 Manasseh G Sevag
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 03:08
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/63; A61K31/635; A61K31/33; A61K31/395; A61K31/435; A61K31/47; A61K31/54; A61K31/55; A61K31/65; A61K31/70
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
53 words
A composition for killing bacteria by physical contact therewith consisting essentially of (1) an effective amount of a bactericidal component selected from the class consisting of sulfathiazole, chloromycetin, streptomycin, penicillin, erythromycin, tetracycline, chloramphenicol and novobiocin, and (2) an amount in the range of 20- 200 micrograms of quinacrine hydrochloride, in sterile aqueous solution.
Claim 2
Dependent Claim
32 words
A composition for killing bacteria by physical contact, comprising a sterile aqueous solution of about 10- 100 micrograms per milliliter or streptomycin and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
Claim 3
Dependent Claim
32 words
A composition for killing bacteria by physical contact, comprising a sterile aqueous solution of about 0.01- 1.0 unit of penicillin per milliliter and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
Claim 4
Dependent Claim
32 words
A composition for killing bacteria by physical contact comprising a sterile aqueous solution of about 0.1- 10 micrograms per milliliter of novobiocin and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
Claim 5
Dependent Claim
30 words
A composition for killing bacteria by physical contact comprising a sterile aqueous solution of about 0.1-10.0 micrograms per milliliter of erythromycin and about 20-200 micrograms per milliliter of quinacrine hydrochloride.
Claim 6
Dependent Claim
32 words
A composition for killing bacteria by physical contact comprising a sterile aqueous solution of about 0.1- 10.0 micrograms per milliliter of tetracycline and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
Claim 7
Dependent Claim
32 words
A composition for killing bacteria by physical contact comprising a sterile aqueous solution of about 0.1- 10 micrograms per milliliter of chloramphenicol and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
Claim 8
Dependent Claim
32 words
A composition for killing bacteria by physical contact comprising a sterile aqueous solution of about 0.1- 100 micrograms per milliliter of sulfathiazole and about 20- 200 micrograms per milliliter of quinacrine hydrochloride.
References Cited (Backward Citations)
US2579185A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-09-05 | 1976-03-06 | 1976-09-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-09-05 | 1980-03-06 | 1980-09-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-09-05 | 1984-03-06 | 1984-09-05 | $7700.00 | Window Closed / Lapsed |