US3700697A
Expired / Lapsed
US
⏱️ 0.0 years remaining
(2,3-dihydro-2-benzofuranylmethyl) guanidines and their preparation
Assignee: STWB Inc
•
Filing: 1968-04-22
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Granted: 1972-10-24
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Expires: 1988-04-22
Abstract
Abstract (2,3-Dihydro-2-benzo-furanylmethyl)guanidines and (2,3-dihydro2-benzofuranylmethyl)-aminoguanidines, having anti-hypertensive activity, are prepared by reacting the corresponding respective 2,3-dihydro-2-benzo-furanylmethylamine or (2,3-dihydro-2benzofuranylmethyl)hydrazine with a guanylating agent, e.g., 2(lower-alkyl)-2-thiopseudourea or cyanamide. Preparation of various intermediates are given, e.g., 2,3-dihydro-2benzofuranylmethyl halides, N-(2,3-dihydro-2benzofuranylmethyl)phthalimides, 2,3-dihydro-2benzofuranylmethylamines and (2,3-dihydro-2benzofuranylmethyl)hydrazines.
Inventors
- 👤 Denis M Bailey
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-05 01:47
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D307/81
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
12 words
(2,3-dihydro-5,7-dimethyl-2-benzofuranylmethyl)-guanidine according to claim 1 having formula I where R is methyl.
Claim 2
Dependent Claim
12 words
(2,3-dihydro-7-methyl-2-benzofuranylmethyl)guanidine according to claim 1 having formula I where R is hydrogen.
Claim 3
Dependent Claim
18 words
A method for preparing a compound according to claim 1 which comprises reacting a compound of the formula
Claim 4
Dependent Claim
12 words
A method according to claim 4 where the guanylating agent is 2-(lower-alkyl)-2-thiopseudourea.
Claim 5
Dependent Claim
6 words
A 2-guanidinylmethyl 2,3-dihydrobenzofuran having the formula
Claim 6
Dependent Claim
13 words
The compound claimed in claim 6, in which R is a hydrogen atom.
References Cited (Backward Citations)
DE1202285B
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-10-24 | 1976-04-24 | 1976-10-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-10-24 | 1980-04-24 | 1980-10-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-10-24 | 1984-04-24 | 1984-10-24 | $7700.00 | Window Closed / Lapsed |