US3857940A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Inosine derivatives
Assignee: NEWPORT PHARMA INC US
•
Filing: 1972-12-07
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Granted: 1974-12-31
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Expires: 1992-12-07
Abstract
Abstract Complexes are formed in inosine and aminoalcohols of the formula WHERE R1 and R2 are lower alkyl and n is an integer of 2 to 4. The complexes have pharmacological activity including the ability to restore deteriorated learning and memory behavior. The preferred aminoalcohol is dimethylamino isopropanol. The preferred ratio of inosine to aminoalcohol is 1:3.
Inventors
- 👤 P Gordon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 17:00
CPC Classifications
C; C07; C07H; C07H19/00; C07H19/02; C07H19/04; C07H19/16; A; A61; A61K; A61K31/00; A61K31/70
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
22 words
A METHOD OF IMPROVING MEMORY IN A MAMMAL COMPRISING FEEDIG THE MAMMAL A COMPLEX OF INOSINE WITH A DIALKYLAMINOALKANOL HAVING THE FORMULA:
Claim 2
Independent Claim
22 words
A METHOD OF IMPROVING MEMORY IN A MAMMAL COMPRISING FEEDIG THE MAMMAL A COMPLEX OF INOSINE WITH A DIALKYLAMINOALKANOL HAVING THE FORMULA:
Claim 3
Dependent Claim
22 words
A method according to claim 1 wherein the aminoalcohol of the complex is selected from the group consisting of dimethylaminoethanol and dimethylaminoisopropanol.
Claim 4
Dependent Claim
19 words
A method according to claim 2 wherein the mole ratio of inosine to aminoalkanol is from 1:1 to 1:4.
Claim 5
Dependent Claim
24 words
A method according to claim 3 wherein the complex is fed in an amount of 1 to 1000 mg/kg body weight of the mammal.
Claim 6
Independent Claim
22 words
A method of improving memory in a mammal comprising feeding the mammal a mixture of inosine and a dialkylaminoalkanol having the formula
Claim 7
Independent Claim
22 words
A method of improving memory in a mammal comprising feeding the mammal a mixture of inosine and a dialkylaminoalkanol having the formula
Claim 8
Dependent Claim
22 words
A method according to claim 3 wherein the mammal is a rat, mouse, guinea pig, dog, cat, horse, cow, sheep or pig.
Claim 9
Dependent Claim
12 words
A method according to claim 6 wherein the mammal is a rat.
Claim 10
Dependent Claim
16 words
A method according to claim 1 wherein R1 and R2 are methyl and n is 2.
Claim 11
Dependent Claim
16 words
A method according to claim 5, wherein R1 and R2 are methyl and n is 2.
References Cited (Backward Citations)
US3520873A
Cited
US3728450A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-30 | 1978-07-01 | 1978-12-31 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-30 | 1982-07-01 | 1982-12-31 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-30 | 1986-07-01 | 1986-12-31 | $7700.00 | Window Closed / Lapsed |