US3873720A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Nutrient fat emulsion
Assignee: Tanabe Pharma Corp
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Filing: 1974-01-30
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Granted: 1975-03-25
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Expires: 1994-01-30
Abstract
Abstract An aqueous mixture of fat, carbohydrate and amino acids is emulsified with the aid of long-chain fatty acid or its basic amino acid salt and egg-yolk phospholipids. Egg-yolk phospholipids is employed in an amount of 0.05 to 0.3 g per g of fat. Moreover, long-chain fatty acid or its basic amino acid salt is employed in an amount of 0.02 to 3.0 g per g of phospholipids. The emulsification is carried out under a pressure of more than 300 kg/cm2. A stable nutrient fat emulsion in which fat particles have the average diameter of less than 0.5 Mu is obtained.
Inventors
- 👤 Akira Suzuki
- 👤 Hiroshi Miura
- 👤 Katsuya Sawada
- 👤 Yoshiyuki Koida
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 04:06
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0029; A23; A23D; A23D7/00; A23D7/005; A23D7/0053; A23L; A23L33/00; A23L33/10; A23L33/17; A23L33/175; A23L35/00; A23L35/10; A61K31/00; A61K31/21; A61K31/215; A61K31/22; A61K31/23; A61K31/33; A61K31/395; A61K31/41; A61K31/415
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
160 words
AN OIL-IN-WATER EMULSION COMPRISING 1-15 W/V% BASED ON THE EMULSION OF A FAT SELECTED FROM THE GROUP CONSISTING OF SESAME SEED OIL, PEANUT OIL, OLIVE OIL, SAFFLOWER OIL AND SOYBEAN OIL, 1-30 W/V% BASED ON THE EMULSION OF A CARBOHYDRATE SELECTED FROM THE GROUP CONSISTING OF XYLITOL AND SORBITOL, 1-15 W/V% BASED ON THE EMULSION OF AT LEAST 2 AMINO ACIDS SELECTED FROM THE GROUP CONSISTING OF L-ISOLEUCINE, L-LEUCINE, L-LYSINE, L-VALINE, L-METHIONINE, L-THREONINE, L-TRYPTOPHAN, LPHENYLALANINE, L-ALANINE, L-PROLINE, L-GLUTAMIC, LASPARTIC ACID, L-SERINE, L-ARGININE, L-HISTIDINE, L-TYROSINE, L-CYSTEIN, L-CYSTINE AND GLYCINE, 0.05 TO 0.30 G PER G OF FAT OF EGG-YOLK PHOSPHOLIPIDS, 0.02 TO 3.0 PER G OF PHOSPHOLIPIDS OF FATTY ACID HAVING 12 TO 20 CARBON ATOMS OR A SALT THEREOF WITH ARGINE, LYSINE OR ORNITHINE AND A SUFFICIENT AMOUNT OF WATER TO BRING THE EMULSION UP TO 100 W/V%, SAID FAT CONSTITUTING THE DISPERSED PHASE OF SAID EMULSION, PARTICLES OF DISPERSED FAT HAVING AN AVERAGE DIAMETER OF LESS THAN 0.5 U.
Claim 2
Dependent Claim
160 words
AN OIL-IN-WATER EMULSION COMPRISING 1-15 W/V% BASED ON THE EMULSION OF A FAT SELECTED FROM THE GROUP CONSISTING OF SESAME SEED OIL, PEANUT OIL, OLIVE OIL, SAFFLOWER OIL AND SOYBEAN OIL, 1-30 W/V% BASED ON THE EMULSION OF A CARBOHYDRATE SELECTED FROM THE GROUP CONSISTING OF XYLITOL AND SORBITOL, 1-15 W/V% BASED ON THE EMULSION OF AT LEAST 2 AMINO ACIDS SELECTED FROM THE GROUP CONSISTING OF L-ISOLEUCINE, L-LEUCINE, L-LYSINE, L-VALINE, L-METHIONINE, L-THREONINE, L-TRYPTOPHAN, LPHENYLALANINE, L-ALANINE, L-PROLINE, L-GLUTAMIC, LASPARTIC ACID, L-SERINE, L-ARGININE, L-HISTIDINE, L-TYROSINE, L-CYSTEIN, L-CYSTINE AND GLYCINE, 0.05 TO 0.30 G PER G OF FAT OF EGG-YOLK PHOSPHOLIPIDS, 0.02 TO 3.0 PER G OF PHOSPHOLIPIDS OF FATTY ACID HAVING 12 TO 20 CARBON ATOMS OR A SALT THEREOF WITH ARGINE, LYSINE OR ORNITHINE AND A SUFFICIENT AMOUNT OF WATER TO BRING THE EMULSION UP TO 100 W/V%, SAID FAT CONSTITUTING THE DISPERSED PHASE OF SAID EMULSION, PARTICLES OF DISPERSED FAT HAVING AN AVERAGE DIAMETER OF LESS THAN 0.5 U.
Claim 3
Dependent Claim
44 words
The emulsion of claim 1 in which said egg-yolk phospholipids are present in an amount of 0.1 to 0.25 g per g of fat, and said fatty acid or its salt is present in an amount of 0.05 to 2.5 per g of phospholipids.
Claim 4
Dependent Claim
13 words
The oil-in-water emulsion claimed in claim 1, wherein said fat is soybean oil.
Claim 5
Dependent Claim
13 words
The oil-in-water emulsion clAimed in claim 2, wherein said fat is soybean oil.
Claim 6
Independent Claim
183 words
A method of preparing an oil-in-water emulsion which comprises dispersing an aqeuous mixture, said aqueous mixture containing at least 1 to 15 w/v% based on the emulsion of a fat selected from the group of sesame seed oil, peanut oil, olive oil, safflower oil or soybean oil, 1 to 30 w/v% based on the emulsion of a carbohydrate selected from the group of xylitol and sorbitol and 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine, and glycine, with an homogenizer under a pressure of more than 300 kg/cm2 with the aid of a mixture of 0.05 to 0.30 g per g of fat of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine or ornithine, to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
Claim 7
Independent Claim
183 words
A method of preparing an oil-in-water emulsion which comprises dispersing an aqeuous mixture, said aqueous mixture containing at least 1 to 15 w/v% based on the emulsion of a fat selected from the group of sesame seed oil, peanut oil, olive oil, safflower oil or soybean oil, 1 to 30 w/v% based on the emulsion of a carbohydrate selected from the group of xylitol and sorbitol and 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine, and glycine, with an homogenizer under a pressure of more than 300 kg/cm2 with the aid of a mixture of 0.05 to 0.30 g per g of fat of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine or ornithine, to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
Claim 8
Dependent Claim
40 words
The method according to claim 5, wherein the egg-yolk phospholipids and fatty acid or its salt are employed in an amount of 0.1 to 0.25 g per g of fat and 0.05 to 2.5 g per g of phospholipids, respectively.
Claim 9
Dependent Claim
16 words
The method according to claim 5, wherein the pressure is adjusted to 350 to 550 kg/cm2.
Claim 10
Dependent Claim
49 words
The method according to claim 5, wherein egg-yolk phospholipids and fatty acid or its salt are employed in an amount of 0.05 to 0.30 g per g of fat and 0.02 to 3.0 g per g of phospholipids, respectively, and the pressure is adjusted to 350 to 550 kg/cm2.
Claim 11
Dependent Claim
22 words
The method according to claim 5, wherein said fat is soybean oil, and the pressure is adjusted to 350 to 550 kg/cm2.
Claim 12
Independent Claim
171 words
A method of preparing an oil-in-water emulsion which comprises dispersing into water 1 to 15 w/v% based on the emulsion of soybean oil, 0.05 to 0.30 g per g of soybean oil of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of a fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine or ornithine, dispersing the aqueous mixture with a homogenizer under a pressure of more than 300 kg/cm2, adding 1 to 30 w/v% based on the emulsion of xylitol or sorbitol and 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine, and glycine thereto, and again dispersing the resultant aqueous mixture with an homogenizer under a pressure of more than 300 kg/cm2 to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
Claim 13
Independent Claim
171 words
A method of preparing an oil-in-water emulsion which comprises dispersing into water 1 to 15 w/v% based on the emulsion of soybean oil, 0.05 to 0.30 g per g of soybean oil of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of a fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine or ornithine, dispersing the aqueous mixture with a homogenizer under a pressure of more than 300 kg/cm2, adding 1 to 30 w/v% based on the emulsion of xylitol or sorbitol and 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine, and glycine thereto, and again dispersing the resultant aqueous mixture with an homogenizer under a pressure of more than 300 kg/cm2 to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
Claim 14
Independent Claim
169 words
A method of preparing an oil-in-water emulsion which comprises dispersing into water 1 to 15 w/v% based on the emulsion of soybean oil, 1 to 30 w/v% based on the emulsion of xylitol or sorbitol, 0.05 to 0.30 g per g of soybean oil of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine, or ornithine, dispersing the aqueous mixture with an homogenizer under a pressure of more than 300 kg/cm2, adding 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group consisting of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine and glycine, and again dispersing the resultant aqueous mixture with the homogenizer under a pressure of more than 300 kg/cm2 to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
Claim 15
Independent Claim
169 words
A method of preparing an oil-in-water emulsion which comprises dispersing into water 1 to 15 w/v% based on the emulsion of soybean oil, 1 to 30 w/v% based on the emulsion of xylitol or sorbitol, 0.05 to 0.30 g per g of soybean oil of egg-yolk phospholipids and 0.02 to 3.0 g per g of phospholipids of fatty acid having 12 to 20 carbon atoms or a salt thereof with arginine, lysine, or ornithine, dispersing the aqueous mixture with an homogenizer under a pressure of more than 300 kg/cm2, adding 1 to 15 w/v% based on the emulsion of at least two amino acids selected from the group consisting of L-isoleucine, L-leucine, L-lysine, L-valine, L-methionine, L-threonine, L-tryptophan, L-phenylalanine, L-alanine, L-proline, L-glutamic acid, L-aspartic acid, L-serine, L-arginine, L-histidine, L-tyrosine, L-cystein, L-cystine and glycine, and again dispersing the resultant aqueous mixture with the homogenizer under a pressure of more than 300 kg/cm2 to give the oil-in-water emulsion in which fat particles have an average diameter of less than 0.5 Mu .
References Cited (Backward Citations)
US2853419A
Cited
US3169094A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-03-24 | 1978-09-23 | 1979-03-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-03-24 | 1982-09-23 | 1983-03-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-03-24 | 1986-09-23 | 1987-03-25 | $7700.00 | Window Closed / Lapsed |