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US3900481A Expired / Lapsed US ⏱️ 0.0 years remaining

Derivatives of pyrrolidine and piperidine

Assignee: Riker Laboratories Inc
•
Filing: 1974-04-01
•
Granted: 1975-08-19
•
Expires: 1994-04-01
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Abstract

Abstract Certain compounds in which a carbon atom of a pyrrolidine or piperidine ring is bonded directly or through a methylene group to the nitrogen of a substituted benzamido group, and their pharmaceutically acceptable salts, are found to be active as antiarrhythmic agents.

Inventors

  • 👤 Elden H Banitt
  • 👤 William R Bronn

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 17:44
CPC Classifications
C; C07; C07D; C07D213/00; C07D213/02; C07D213/04; C07D213/24; C07D213/36; C07D213/40; A; A61; A61P; A61P25/00; A61P25/02; A61P25/04; A61P9/00; A61P9/06; C07D207/00; C07D207/02; C07D207/04; C07D207/08; C07D207/09; C07D207/10; C07D207/14; C07D211/00; C07D211/04; C07D211/06; C07D211/08; C07D211/18; C07D211/26; C07D211/36; C07D211/56; C07D211/58; C07D213/60; C07D213/72; C07D213/75

Claims Analysis

Total Claims: 17
Claim 1
Independent Claim 5 words
A COMPOUND OF THE FORMULA:
Claim 2
Dependent Claim 5 words
A COMPOUND OF THE FORMULA:
Claim 3
Dependent Claim 10 words
A compound according to claim 1 wherein p is 2.
Claim 4
Dependent Claim 21 words
A compound according to claim 1 wherein Rf is trifluoromethyl, n is two and the substituents are in the 2,5 positions.
Claim 5
Dependent Claim 5 words
A compound of the formula:
Claim 6
Dependent Claim 5 words
A compound of the formula:
Claim 7
Dependent Claim 21 words
A compound according to claim 4 wherein Rf is trifluoromethyl, n is two and the substituents are in the 2,5 positions.
Claim 8
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-((1-methyl-2-piperidyl)methyl)benzamide, or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 9
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-(3-piperidyl)benzamide or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 10
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-((1-ethyl-2-piperidyl)methyl)benzamide or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 11
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-((1-ethyl-2-pyrrolidyl)methyl)benzamide, or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 12
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-(1-(2-piperidyl)ethyl)benzamide or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 13
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-((6-methyl-2-piperidyl)methyl)benzamide or a pharmaceutically acceptable salt thereof according to claiM 1.
Claim 14
Dependent Claim 6 words
2,5-Bis(2,2,2-trifluoroethoxy)-N-((6-methyl-2-piperidyl)methyl)benzamide hydrochloride according to claim 11.
Claim 15
Dependent Claim 13 words
The compound 2,5-bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide or a pharmaceutically acceptable salt thereof according to claim 1.
Claim 16
Dependent Claim 6 words
2,5-Bis(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)benzamide hydrochloride according to claim 13.
Claim 17
Dependent Claim 12 words
A compound according to claim 1 which has an asymmetric carbon atom.

References Cited (Backward Citations)

US3594417A Cited
US3655728A Cited
US3719687A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-08-18 1979-02-17 1979-08-19 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-08-18 1983-02-17 1983-08-19 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-08-18 1987-02-17 1987-08-19 $7700.00 Window Closed / Lapsed

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