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US3905979A Expired / Lapsed US ⏱️ 0.0 years remaining

Diazabicyclooctanes and diazabicycloheptanes

Assignee: SRI International Inc
•
Filing: 1974-05-09
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Granted: 1975-09-16
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Expires: 1994-05-09
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Abstract

Abstract Twelve analogs of diethylcarbamazine as prepared by acylation of 3- and 8-methyl-3,8-diazabicyclo(3.2.1)octane, 2-methyl-2,5diazabicyclo(2.2.2)octane, and 2-methyl-2,5diazabicyclo(2.2.1)heptane with diethylcarbamyl chloride, ethyl chloroformate, ethyl isocyanate, and cyclohexanecarbonyl chloride. These compounds are formally derived from diethylcarbamazine in possessing two- or one-carbon bridges over the piperazine ring. The compounds have utility as antifilarial agents and as bronchodilators.

Inventors

  • 👤 David W Henry
  • 👤 Priscilla A Sturm

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-01 14:54
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/08; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16; C07D487/00; C07D487/02; C07D487/08

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 5 words
A COMPOUND HAVING THE STRUCTURE
Claim 2
Dependent Claim 5 words
A COMPOUND HAVING THE STRUCTURE
Claim 3
Dependent Claim 17 words
The compound of claim 1 which is 2-(N,N-Diethylcarbamyl-5-methyl-2,5-diazabicyclo(2.2.2)octane; together with the acid addition salts of said compound.
Claim 4
Dependent Claim 17 words
The compound of claim 1 which is 2-carbethoxy-5-methyl-2,5-diazabicyclo(2.2.2)octane; together with the acid addition salts of said compound.
Claim 5
Dependent Claim 17 words
The compound of claim 1 which is 2-(N-ethylcarbamyl)-5-methyl-2,5-diazabicyclo(2.2.2)octane; together with the acid addition salts of said compound.

References Cited (Backward Citations)

No citation records indexed.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-09-15 1979-03-17 1979-09-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-09-15 1983-03-17 1983-09-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-09-15 1987-03-17 1987-09-16 $7700.00 Window Closed / Lapsed

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