US3908012A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Arylpyrimidines-inhibitors of platelet aggregation and bronchodilators
Assignee: Pfizer Inc
•
Filing: 1973-06-19
•
Granted: 1975-09-23
•
Expires: 1993-06-19
Abstract
Abstract 4-Amino-6-arylpyrimidines and salts thereof, a novel class of inhibitors of platelet aggregation and bronchodilators in mammals, and 4-hydroxy-6-arylpyrimidines as useful intermediates.
Inventors
- 👤 Angelis Gerald George De
- 👤 Hans-Jurgen Ernst Hess
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 16:34
CPC Classifications
C; C07; C07D; C07D495/00; C07D495/02; C07D495/04
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
44 words
A METHOD OF INHIBITING PLATELET AGGREGATION IN THE BLOOD OF HUMANS WHICH COMPRISES ADMINISTERING TO SAID HUMANS AN EFFECTIVE AMOUNT SUFFICIENT TO INHIBIT PLATELET AGGREGATION IN THE BLOOD OF THE HUMANS OF A COMPOUND SELECTED FROM THE GROUP CONSISTING OF THOSE OF THE FORMULA:
Claim 2
Independent Claim
44 words
A METHOD OF INHIBITING PLATELET AGGREGATION IN THE BLOOD OF HUMANS WHICH COMPRISES ADMINISTERING TO SAID HUMANS AN EFFECTIVE AMOUNT SUFFICIENT TO INHIBIT PLATELET AGGREGATION IN THE BLOOD OF THE HUMANS OF A COMPOUND SELECTED FROM THE GROUP CONSISTING OF THOSE OF THE FORMULA:
Claim 3
Dependent Claim
23 words
The method of claim 1 wherein R1 is ethyl, R2 is alkyl containing from 1 to 4 carbon atoms and R3 is hydrogen.
Claim 4
Dependent Claim
10 words
The method of claim 2 wherein said compound is 4-diethylamino-6-(p-methoxyphenyl)pyrimidine.
Claim 5
Dependent Claim
10 words
The method of claim 2 wherein said compound is 4-diethylamino-6-phenylpyrimidine.
Claim 6
Dependent Claim
10 words
The method of claim 2 wherein said compound is 4-(ethyl-n-propylamino)-6-phenylpyrimidine.
Claim 7
Dependent Claim
10 words
The method of claim 2 wherein said compound is 4-diethylamino-6-(2-thiEnyl)pyrimidine.
Claim 8
Dependent Claim
10 words
The method of claim 2 wherein said compound is 4-diethylamino-6-(m-dimethylaminophenyl)pyrimidine.
Claim 9
Dependent Claim
23 words
The method of claim 1 wherein Ar is phenyl, R1 is alkyl containing from 1 to 4 carbon atoms and R3 is hydrogen.
Claim 10
Dependent Claim
10 words
The method of claim 8 wherein said compound is 4-(ethyl(2-hydroxyethyl)amino)-6-phenylpyrimidine.
Claim 11
Dependent Claim
10 words
The method of claim 8 wherein said compound is 4-ethylamino-6-phenylpyrimidine.
Claim 12
Dependent Claim
16 words
The method of claim 1 wherein Ar is phenyl, R1 is 2,2,2-trifluoroethyl and R3 is hydrogen.
Claim 13
Dependent Claim
10 words
The method of claim 11 wherein said compound is 4-(2,2,2-trifluoroethylamino)-6-phenylpyrimidine.
Claim 14
Dependent Claim
23 words
The method of claim 1 wherein R1 and R2 are each ethyl and R3 is alkyl containing from 1 to 3 carbon atoms.
Claim 15
Dependent Claim
10 words
The method of claim 13 wherein said compound is 4-diethylamino-5-methyl-6-phenylpyrimidine.
Claim 16
Dependent Claim
10 words
The method of claim 13 wherein said compound is 4-diethylamino-5-ethyl-6-phenylpyrimidine.
References Cited (Backward Citations)
US2418548A
Cited
US2735225A
Cited
US1915334A
Cited
US2075359A
Cited
US2425320A
Cited
US2606155A
Cited
US3707560A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1978-09-22 | 1979-03-24 | 1979-09-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1982-09-22 | 1983-03-24 | 1983-09-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1986-09-22 | 1987-03-24 | 1987-09-23 | $7700.00 | Window Closed / Lapsed |