Patent US808884A successfully refreshed from Google Patents.
US3944584A
Expired / Lapsed
US
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Steroidal (16α,17-d)cyclohexenes
Assignee: ER Squibb and Sons LLC
•
Filing: 1975-02-03
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Granted: 1976-03-16
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Expires: 1995-02-03
Abstract
Abstract A series of novel steroidal[ 16α, 17-d]cyclohexenes having a 9-fluoro group is disclosed herein for use as anti-inflammatory agents.
Inventors
- 👤 Sam T. Chao
- 👤 Christopher M. Cimarusti
- 👤 Ravi K. Varma
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 20:15
CPC Classifications
C; C07; C07J; C07J53/00; C07J53/002; A; A61; A61P; A61P29/00
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
62 words
A steroid having the formula ##SPC3## or the 1,2-dehydro derivative thereof, wherein R 1 is hydrogen, hydroxy, halogen, or acyloxy; R 2 and R 3 are the same or different and are hydrogen, alkyl, or aryl; R 4 is hydrogen and R 5 is hydroxy, or together R 4 and R 5 are =O; and R 6 is hydrogen, methyl, or fluorine.
Claim 2
Dependent Claim
62 words
A steroid having the formula ##SPC3## or the 1,2-dehydro derivative thereof, wherein R 1 is hydrogen, hydroxy, halogen, or acyloxy; R 2 and R 3 are the same or different and are hydrogen, alkyl, or aryl; R 4 is hydrogen and R 5 is hydroxy, or together R 4 and R 5 are =O; and R 6 is hydrogen, methyl, or fluorine.
Claim 3
Dependent Claim
16 words
A steroid in accordance with claim 1 wherein R 2 and R 3 are both hydrogen.
Claim 4
Dependent Claim
16 words
A steroid in accordance with claim 1 wherein R 2 and R 3 are both alkyl.
Claim 5
Dependent Claim
17 words
A steroid in accordance with claim 1 wherein R 4 is hydrogen and R 5 is hydroxy.
Claim 6
Dependent Claim
16 words
A steroid in accordance with claim 1 wherein together R 4 and R 5 are =O.
Claim 7
Dependent Claim
12 words
A steroid in accordance with claim 1 wherein R 6 is hydrogen.
Claim 8
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 9-fluoro-11β,21-dihydroxy-1',2'dimethylpregna-1,4-dieno[16α,17-d]cyclohexene-3,20-dione.
Claim 9
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 21-(acetyloxy)-9-fluoro-11β-hydroxy-1',2'-dimethylpregna-1,4-dieno[16α,17-d]cyclohexene-3,20-dione.
Claim 10
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 21-chloro-9-fluoro-11β-hydroxy-1',2'-dimethylpregna-1,4-dieno[16.alpha.,17-d]cyclohexene-3,20-dione.
Claim 11
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 9-fluoro-11β,21-dihydroxypregna-1,4-dieno[16α,17-d]-cyclohexene-3,20-dione.
Claim 12
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 21-(acetyloxy)-9-fluoro-11β-hydroxypregna-1,4-dieno[16α,17-d]cyclohexene-3,20-dione.
Claim 13
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 21-chloro-9-fluoro-11β-hydroxypregna-1,4-dieno[16α,17-d]cyclohexene-3,20-dione.
Claim 14
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 9-fluoro-1',2'-dimethylpregn-4-eno[16α,17-d]cyclohexene-3,11,20-trione.
Claim 15
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 9-fluoro-11β,21-dihydroxy-2'-phenylpregna-1,4-dieno[16α,17-d]cyclohexene-3,20-dione.
Claim 16
Dependent Claim
11 words
The steroid in accordance with claim 1 having the name 21-(acetyloxy)-9-fluoro-11β-hydroxy-2'-phenylpregna-1,4-dieno[16.alpha.,17-d]cyclohexene-3,20-dione.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-03-16 | 1979-09-15 | 1980-03-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-03-16 | 1983-09-15 | 1984-03-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-03-16 | 1987-09-15 | 1988-03-16 | $7700.00 | Window Closed / Lapsed |