US3947445A
Expired / Lapsed
US
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Diazabicyclooctanes and diazabicycloheptanes
Assignee: SRI International Inc
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Filing: 1975-08-21
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Granted: 1976-03-30
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Expires: 1995-08-21
Abstract
Abstract Twelve analogs of diethylcarbamazine as prepared by acylation of 3- and 8-methyl-3,8-diazabicyclo[3.2.1]octane, 2-methyl-2,5-diazabicyclo[2.2.2]octane, and 2-methyl-2,5-diazabicyclo [2.2.1]heptane with diethylcarbamyl chloride, ethyl chloroformate, ethyl isocyanate, and cyclohexanecarbonyl chloride. These compounds are formally derived from diethylcarbamazine in possessing two- or one-carbon bridges over the piperazine ring. The compounds have utility as antifilarial agents and as bronchodilators.
Inventors
- 👤 David W. Henry
- 👤 Priscilla A. Sturm
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 08:47
CPC Classifications
C; C07; C07D; C07D471/00; C07D471/02; C07D471/08; C07D487/00; C07D487/02; C07D487/08
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
31 words
A compound having the structure ##SPC3## wherein R 4 represents --CON(C 2 H 5 ) 2 or --COOC 2 H 5 ; together with the acid addition salts of said compounds.
Claim 2
Dependent Claim
31 words
A compound having the structure ##SPC3## wherein R 4 represents --CON(C 2 H 5 ) 2 or --COOC 2 H 5 ; together with the acid addition salts of said compounds.
Claim 3
Dependent Claim
17 words
The compound of claim 1 which is 2-(N,N-diethylcarbamyl)-5-methyl-2,5-diazabicyclo[2.2.1]heptane; together with the acid addition salts of said compound.
Claim 4
Dependent Claim
17 words
The compound of claim 1 which is 2-carbethoxy-5-methyl-2,5-diazabicyclo[2.2.1]heptane; together with the acid addition salts of said compound.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-03-30 | 1979-09-29 | 1980-03-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-03-30 | 1983-09-29 | 1984-03-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-03-30 | 1987-09-29 | 1988-03-30 | $7700.00 | Window Closed / Lapsed |