US3963722A
Expired / Lapsed
US
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Magnesium halide derivatives of tetrahydroquinolines
Assignee: John Wyeth and Brother Ltd
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Filing: 1974-11-22
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Granted: 1976-06-15
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Expires: 1994-11-22
Abstract
Abstract The invention relates to magnesium halide derivatives of tetrahydroquinolines and related compounds. These are intermediates useful in the preparation of anti-ulcer agents.
Inventors
- 👤 Adrian Charles Ward Curran
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 04:57
CPC Classifications
C; C07; C07D; C07D221/00; C07D221/02; C07D221/04; C07D215/00; C07D215/02; C07D215/16; C07D215/48; C07D221/06; C07D221/16; C07F; C07F3/00; C07F3/003; C07F3/02
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
110 words
A compound of formula (II) ##SPC7## wherein R 1 , r 2 and R 6 are independently hydrogen, trifluoromethyl, alkyl of 1 to 6 carbon atoms, phenylalkyl of 7 to 12 carbon atoms, phenyl, alkylphenyl of 7 to 12 carbon atoms, alkoxyphenyl of 7 to 12 carbon atoms, halophenyl, nitrophenyl or trifluoromethylphenyl; R 7 is hydrogen, alkyl of 1 to 6 carbon atoms, gem-dimethyl (at the 5, 6 or 7 position), phenylalkyl of 7 to 12 carbon atoms, and Hal represents chlorine, bromine or iodine, with the proviso that when R 1 and R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups.
Claim 2
Dependent Claim
110 words
A compound of formula (II) ##SPC7## wherein R 1 , r 2 and R 6 are independently hydrogen, trifluoromethyl, alkyl of 1 to 6 carbon atoms, phenylalkyl of 7 to 12 carbon atoms, phenyl, alkylphenyl of 7 to 12 carbon atoms, alkoxyphenyl of 7 to 12 carbon atoms, halophenyl, nitrophenyl or trifluoromethylphenyl; R 7 is hydrogen, alkyl of 1 to 6 carbon atoms, gem-dimethyl (at the 5, 6 or 7 position), phenylalkyl of 7 to 12 carbon atoms, and Hal represents chlorine, bromine or iodine, with the proviso that when R 1 and R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups.
Claim 3
Dependent Claim
99 words
A compound of formula ##SPC8## wherein R 1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl, R 2 is hydrogen or alkyl of 1 to 6 carbon atoms, R 6 is hydrogen or alkyl of 1 to 6 carbon atoms, R 7 is hydrogen, alkyl of 1 to 6 carbon atoms or gem dimethyl (in the 5, 6 or 7 position) and Hal is chlorine, bromine, or iodine with the proviso that when R 1 and R 2 or R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups.
Claim 4
Dependent Claim
99 words
A compound of formula ##SPC8## wherein R 1 is hydrogen, alkyl of 1 to 6 carbon atoms or phenyl, R 2 is hydrogen or alkyl of 1 to 6 carbon atoms, R 6 is hydrogen or alkyl of 1 to 6 carbon atoms, R 7 is hydrogen, alkyl of 1 to 6 carbon atoms or gem dimethyl (in the 5, 6 or 7 position) and Hal is chlorine, bromine, or iodine with the proviso that when R 1 and R 2 or R 2 and R 6 are both alkyl they are selected from normal and secondary alkyl groups.
Claim 5
Dependent Claim
27 words
A compound of claim 2 of the formula ##SPC9## wherein R 1 , R 2 or R 6 is methyl and Hal is chlorine, bromine, or iodine.
Claim 6
Dependent Claim
9 words
The compound of claim 3 which is 3-methyl-5,6,7,8-tetrahydroquinoline-8-magnesium bromide.
References Cited (Backward Citations)
DE2352585A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-06-15 | 1979-12-15 | 1980-06-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-06-15 | 1983-12-15 | 1984-06-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-06-15 | 1987-12-15 | 1988-06-15 | $7700.00 | Window Closed / Lapsed |