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US3971773A
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US
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Steroidal 9,11-dihalo-[16α,17-b]1,4-dioxanes
Assignee: ER Squibb and Sons LLC
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Filing: 1975-06-02
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Granted: 1976-07-27
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Expires: 1995-06-02
Abstract
Abstract A series of novel steroidal 9,11β-dihalo-[16α,17-b]-1,4-dioxanes is disclosed herein. These compounds are useful as anti-inflammatory agents.
Inventors
- 👤 Christopher M. Cimarusti
- 👤 Frank L. Weisenborn
- 👤 Seymour D. Levine
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-06 11:10
CPC Classifications
C; C07; C07J; C07J17/00; A; A61; A61P; A61P17/00; A61P29/00; C07J31/00; C07J31/006; C07J5/00; C07J5/0046; C07J5/0061; C07J5/0092; C07J71/00; C07J71/0005
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
73 words
A steroid having the structure ##SPC20## and the 1,2-dehydro and 6,7-dehydro derivatives thereof, wherein Z is hydrogen, hydroxy, ##EQU13## or halogen; X is chlorine or fluorine; A 1 is --CH 2 --CH 2 --, ##EQU14## ##EQU15## or ##EQU16## R 1 is hydrogen, alkyl or aryl; R 2 is hydrogen or alkyl; R 3 is alkyl, cycloalkyl or aryl; and P and Q are independent of each other and are hydrogen, methyl or halogen.
Claim 2
Dependent Claim
73 words
A steroid having the structure ##SPC20## and the 1,2-dehydro and 6,7-dehydro derivatives thereof, wherein Z is hydrogen, hydroxy, ##EQU13## or halogen; X is chlorine or fluorine; A 1 is --CH 2 --CH 2 --, ##EQU14## ##EQU15## or ##EQU16## R 1 is hydrogen, alkyl or aryl; R 2 is hydrogen or alkyl; R 3 is alkyl, cycloalkyl or aryl; and P and Q are independent of each other and are hydrogen, methyl or halogen.
Claim 3
Dependent Claim
16 words
A steroid in accordance with claim 1 wherein A 1 is --CH 2 --CH 2 --.
Claim 4
Dependent Claim
12 words
A steroid in accordance with claim 1 wherein A 1 is ##EQU17##
Claim 5
Dependent Claim
12 words
A steroid in accordance with claim 1 wherein A 1 is ##EQU18##
Claim 6
Dependent Claim
12 words
A steroid in accordance with claim 1 wherein A 1 is ##EQU19##
Claim 7
Dependent Claim
12 words
A steroid in accordance with claim 1 wherein A 1 is ##EQU20##
Claim 8
Dependent Claim
11 words
A steroid in accordance with claim 1 wherein X is chlorine.
Claim 9
Dependent Claim
11 words
A steroid in accordance with claim 1 wherein X is fluorine.
Claim 10
Dependent Claim
14 words
A steroid in accordance with claim 1 wherein P and Q are each hydrogen.
Claim 11
Dependent Claim
12 words
The steroid in accordance with claim 1 having the name 9,11β-dichloro-21-hydroxypregna-1,4-dieno[16α,17-b][1,4]dioxane-3,20-dione, 21-acetate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-07-27 | 1980-01-26 | 1980-07-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-07-27 | 1984-01-26 | 1984-07-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-07-27 | 1988-01-26 | 1988-07-27 | $7700.00 | Window Closed / Lapsed |