US3972900A
Expired / Lapsed
US
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7-Substituted benzofuran derivatives
Assignee: Hoffmann La Roche Inc
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Filing: 1975-09-15
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Granted: 1976-08-03
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Expires: 1995-09-15
Abstract
Abstract The present disclosure is concerned with new benzofuran derivatives and a process for the preparation thereof. The present benzofuran derivatives are useful as β-adrenergic blocking agents.
Inventors
- 👤 Graham Alwyn Fothergill
- 👤 John Mervyn Osbond
- 👤 James Charles Wickens
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 06:40
CPC Classifications
C; C07; C07D; C07D307/00; C07D307/77; C07D307/78; C07D307/79; C07D307/81; A; A61; A61P; A61P25/00; A61P25/02
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
19 words
A compound of the formula ##EQU1##, wherein A is hydroxymethylene or carbonyl, and pharmaceutically acceptable acid addition salts thereof.
Claim 2
Dependent Claim
19 words
A compound of the formula ##EQU1##, wherein A is hydroxymethylene or carbonyl, and pharmaceutically acceptable acid addition salts thereof.
Claim 3
Dependent Claim
8 words
The compound of claim 1 which is 7-(1'-hydroxyethyl)-α-(tertbutylaminomethyl)-2-benzofuranmethanol.
Claim 4
Dependent Claim
8 words
The compound of claim 1 which is 7-acetyl-α-(tertbutylaminomethyl)-2-benzofuranmethanol.
Claim 5
Dependent Claim
18 words
A compound of the formula ##STR18##wherein R is hydrogen or lower alkanoyl and X is chlorine or bromine.
Claim 6
Dependent Claim
18 words
A compound of the formula ##STR18##wherein R is hydrogen or lower alkanoyl and X is chlorine or bromine.
Claim 7
Dependent Claim
8 words
The compound of claim 4 which is 7-(1'-acetoxyethyl)-2-(1'-hydroxy-2'-bromoethyl)benzofuran.
Claim 8
Dependent Claim
11 words
A compound of the formula ##STR19##wherein R 1 is lower alkanoyl.
Claim 9
Dependent Claim
11 words
A compound of the formula ##STR19##wherein R 1 is lower alkanoyl.
Claim 10
Dependent Claim
9 words
The compound of claim 6 which is 7-(1'-acetoxyethyl)-2-benzofuranyl, (tertbutylaminomethyl)-ketone.
References Cited (Backward Citations)
US3340266A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-03 | 1980-02-02 | 1980-08-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-03 | 1984-02-02 | 1984-08-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-03 | 1988-02-02 | 1988-08-03 | $7700.00 | Window Closed / Lapsed |