US3974156A
Expired / Lapsed
US
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2-(Substituted anilino) methylmorpholine compounds
Assignee: Imperial Chemical Industries Ltd
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Filing: 1973-08-10
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Granted: 1976-08-10
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Expires: 1993-08-10
Abstract
Abstract The disclosure relates to new 2-(substituted anilino)-methylmorpholine derivatives which possess sedative activity, to processes for the manufacture of the said morpholine derivatives, and to pharmaceutical compositions containing them. Typical of the morpholine derivatives disclosed is 2-(3-methoxyanilino)methylmorpholine.
Inventors
- 👤 Edwin Harry Paterson Young
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:42
CPC Classifications
C; C07; C07D; C07D265/00; C07D265/28; C07D265/30; A; A61; A61P; A61P25/00; A61P25/24; A61P25/26; C07D303/00; C07D303/02; C07D303/36
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
64 words
A morpholine selected from compounds of the formula: ##SPC10## wherein R 1 is hydrogen or acetyl of up to 4 carbon atoms; R 2 is hydrogen or alkyl of 1 to 6 carbon atoms; R 3 is halogen, alkyl of 1 to 4 carbon atoms, methoxy, methylthio or trifluoromethyl; and R 4 is hydrogen or trifluoromethyl; and the non-toxic, pharmaceutically acceptable acid-addition salts thereof.
Claim 2
Dependent Claim
64 words
A morpholine selected from compounds of the formula: ##SPC10## wherein R 1 is hydrogen or acetyl of up to 4 carbon atoms; R 2 is hydrogen or alkyl of 1 to 6 carbon atoms; R 3 is halogen, alkyl of 1 to 4 carbon atoms, methoxy, methylthio or trifluoromethyl; and R 4 is hydrogen or trifluoromethyl; and the non-toxic, pharmaceutically acceptable acid-addition salts thereof.
Claim 3
Dependent Claim
44 words
A morpholine as claimed in claim 1 wherein R 1 is hydrogen or acetyl; R 2 is hydrogen or methyl, ethyl, n-propyl or i-propyl; R 3 is fluorine, chlorine, methyl, ethyl, n-propyl, n-butyl, methoxy, methylthio or trifluoromethyl and R 4 is hydrogen or trifluoromethyl.
Claim 4
Dependent Claim
18 words
A morpholine as claimed in claim 1 selected from the group consisting of 2-(3-chloroanilino)methylmorpholine, 2-(3-methoxyanilino)methylmorpholine, 2-(3-methylthioanilino)methylmorpholine and 2-(3-trifluoromethylanilino)methylmorpholine.
References Cited (Backward Citations)
GB940035A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-08-10 | 1980-02-09 | 1980-08-10 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-08-10 | 1984-02-09 | 1984-08-10 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-08-10 | 1988-02-09 | 1988-08-10 | $7700.00 | Window Closed / Lapsed |