US3979507A
Expired / Lapsed
US
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Diagnostic system for organ abnormalities
Assignee: Wilson Pharmaceutical and Chemical Corp
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Filing: 1973-11-23
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Granted: 1976-09-07
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Expires: 1993-11-23
Abstract
Abstract A system is provided for the detection and identification of a diseased or impaired organ in a patient through detection and measurement in the patient's blood, or other body fluid specimen, of an antigen which is normally present in healthy organs of the same kind and normally not present in the blood of a healthy person. The system includes a method for producing and purifying an antibody to the antigen, and for utilizing the antibody to detect and measure an antigen in the patient's blood.
Inventors
- 👤 Albert Leroy Baker
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 13:03
CPC Classifications
G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; C; C07; C07K; C07K16/00; C07K16/18; Y; Y10; Y10S; Y10S436/00; Y10S436/80; Y10S436/811
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
84 words
A method of diagnosing a patent for an abnormal condition of a specific organ which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material with respect to said specific organ and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the tissue of said specific organ of a healthy human and substantially free of any antibodies to all antigens present in
Claim 2
Independent Claim
84 words
A method of diagnosing a patent for an abnormal condition of a specific organ which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material with respect to said specific organ and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the tissue of said specific organ of a healthy human and substantially free of any antibodies to all antigens present in
Claim 3
Independent Claim
69 words
A method of diagnosing a patient for an abnormal liver condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the liver tissue of a healthy human, no portion of said diagnostic material being precipitable
Claim 4
Independent Claim
69 words
A method of diagnosing a patient for an abnormal liver condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the liver tissue of a healthy human, no portion of said diagnostic material being precipitable
Claim 5
Independent Claim
80 words
A method of diagnosing a patient for an abnormal kidney condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the kidney tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally present in the blood of a healthy
Claim 6
Independent Claim
80 words
A method of diagnosing a patient for an abnormal kidney condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the kidney tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally present in the blood of a healthy
Claim 7
Independent Claim
69 words
A method of diagnosing a patient for an abnormal heart condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the heart tissue of a healthy human, no portion of said diagnostic material being precipitable
Claim 8
Independent Claim
69 words
A method of diagnosing a patient for an abnormal heart condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the heart tissue of a healthy human, no portion of said diagnostic material being precipitable
Claim 9
Independent Claim
75 words
A method of diagnosing a patient for an abnormal skeletal muscle condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the skeletal muscle tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally
Claim 10
Independent Claim
75 words
A method of diagnosing a patient for an abnormal skeletal muscle condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the skeletal muscle tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally
Claim 11
Independent Claim
79 words
A method of diagnosing a patient for an abnormal pancreas condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the pancreas tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally present in the blood of a
Claim 12
Independent Claim
79 words
A method of diagnosing a patient for an abnormal pancreas condition which comprises taking a sample of blood from said patient, adding to a soluble fraction of said blood a diagnostic material and measuring any reaction product resulting from said addition, said diagnostic material comprising antibodies to at least one antigen normally present in the pancreas tissue of a healthy human, no portion of said diagnostic material being precipitable by any antigen normally present in the blood of a
Claim 13
Dependent Claim
12 words
The method of claim 1, wherein any reaction product resulting from said
Claim 14
Dependent Claim
12 words
The method of claim 1, wherein any reaction product resulting from said
Claim 15
Dependent Claim
12 words
The method of claim 1, wherein any reaction product resulting from said
Claim 16
Dependent Claim
12 words
The method of claim 1, wherein any reaction product resulting from said
Claim 17
Dependent Claim
32 words
The method of claim 1 wherein any reaction product resulting from said addition is detected by a technique utilizing antibodies labeled with a marker selected from the group consisting of fluorescent organic
Claim 18
Dependent Claim
37 words
The method of claim 1 wherein any reaction product resulting from said addition is detected by a method utilizing antigens labeled with a marker selected from the group consisting of fluorescent organic materials, enzymes and radioactive atoms.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-09-07 | 1980-03-08 | 1980-09-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-09-07 | 1984-03-08 | 1984-09-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-09-07 | 1988-03-08 | 1988-09-07 | $7700.00 | Window Closed / Lapsed |