US3984440A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Polyene compounds
Assignee: Hoffmann La Roche Inc
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Filing: 1974-08-07
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Granted: 1976-10-05
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Expires: 1994-08-07
Abstract
Abstract Novel 9-substituted phenyl-3,7-dimethyl-nona-2,4,6,8-tetraenoic acid, -tetraenal or -tetraenol derivatives are described. The subject compounds are useful in the treatment of neoplasias, certain dermatoses and inflammatory and allergic dermatological conditions.
Inventors
- 👤 Werner Bollag
- 👤 Rudolf Ruegg
- 👤 Gottlieb Ryser
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-30 14:55
CPC Classifications
C; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/54; C07F9/5428; C07C; C07C33/00; C07C33/38; C07C45/00; C07C45/51; C07C45/511; C07C45/515; C07C59/00; C07C59/40; C07C59/58; C07C59/64; C07C59/66; C07D; C07D311/00; C07D311/02; C07D311/04; C07D311/58
Claims Analysis
Total Claims: 4
Claim 1
Independent Claim
96 words
A compound having all trans configuration selected from compounds represented by the formula ##SPC6## wherein one adjacent pair of R 1 through R 5 is a oxytrimethylene or 3-oxypropenylene group which may be substituted with one or two lower alkyl groups and the remaining members of R 1 through R 5 each are selected from the group consisting of hydrogen, lower alkyl and lower alkoxy, at least one of said remaining members of R 1 through R 5 being other than hydrogen and R 6 is selected from the group consisting of carboxyl and lower alkoxycarbonyl.
Claim 2
Dependent Claim
96 words
A compound having all trans configuration selected from compounds represented by the formula ##SPC6## wherein one adjacent pair of R 1 through R 5 is a oxytrimethylene or 3-oxypropenylene group which may be substituted with one or two lower alkyl groups and the remaining members of R 1 through R 5 each are selected from the group consisting of hydrogen, lower alkyl and lower alkoxy, at least one of said remaining members of R 1 through R 5 being other than hydrogen and R 6 is selected from the group consisting of carboxyl and lower alkoxycarbonyl.
Claim 3
Dependent Claim
15 words
A compound in accordance with claim 1 wherein said compound is 9-(2,2,5,7,8-pentamethyl-chroman-6-yl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester.
Claim 4
Dependent Claim
13 words
A compound in accordance with claim 1 wherein said compound is 9-(2,2,5,7,8-pentamethyl-chroman-6-yl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid.
References Cited (Backward Citations)
US3524867A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1979-10-05 | 1980-04-05 | 1980-10-05 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1983-10-05 | 1984-04-05 | 1984-10-05 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1987-10-05 | 1988-04-05 | 1988-10-05 | $7700.00 | Window Closed / Lapsed |