US4005160A
Expired / Lapsed
US
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Preparation of α-amino phosphonic acid derivatives
Assignee: Baker Petrolite LLC
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Filing: 1975-05-05
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Granted: 1977-01-25
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Expires: 1995-05-05
Abstract
Abstract This invention relates to a process for preparing α-amino phosphonic acid derivatives which comprises reacting a nitrile with a phosphite ester under hydrogenation conditions; and to the α-amino phosphonic acid derivatives formed and uses thereof.
Inventors
- 👤 Derek Redmore
- 👤 Neil E. S. Thompson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-03 06:48
CPC Classifications
C; C23; C23F; C23F11/00; C23F11/08; C23F11/10; C23F11/167; C23F11/1676; C02; C02F; C02F5/00; C02F5/08; C02F5/10; C02F5/14; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/38; C07F9/40; C07F9/4003; C07F9/4006
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
82 words
A process of preparing an α-aminophosphonic acid derivative which comprises reacting a nitrile with a phosphite ester of the general formula ##STR16##where R 2 and R 3 are alkyl, aryl, aralkyl or where R 2 and R 3 together form a ring structure in a ratio of nitrile to phosphite of about 1:1 to about 1:10 or more at a temperature from about 20° C. to about 150° C. and hydrogen pressures of about 40 to about 200 psi under hydrogenation conditions.
Claim 2
Dependent Claim
82 words
A process of preparing an α-aminophosphonic acid derivative which comprises reacting a nitrile with a phosphite ester of the general formula ##STR16##where R 2 and R 3 are alkyl, aryl, aralkyl or where R 2 and R 3 together form a ring structure in a ratio of nitrile to phosphite of about 1:1 to about 1:10 or more at a temperature from about 20° C. to about 150° C. and hydrogen pressures of about 40 to about 200 psi under hydrogenation conditions.
Claim 3
Dependent Claim
31 words
The process of claim 1 where the α-aminophosphonic acid derivatives formed comprise those of the formula ##STR17## ##STR18##where R 1 is a hydrocarbon group and R 2 is a hydrocarbon group.
Claim 4
Dependent Claim
12 words
The process of claim 2 where R 1 is an arylic group.
Claim 5
Dependent Claim
17 words
The process of claim 3 where the arylic group is a phenyl or a substituted phenyl group.
Claim 6
Dependent Claim
15 words
The process of claim 4 where ##STR19##where X is hydrogen, alkyl, halogen or combinations thereof.
Claim 7
Dependent Claim
10 words
The process of claim 2 where R 1 is aliphatic.
Claim 8
Dependent Claim
19 words
The process of claim 1 where an additional step of hydrolization is carried out to produce an α-aminophosphonic acid.
Claim 9
Dependent Claim
14 words
The process of claim 7 where the hydrolysis is carried out using hydrochloric acid.
Claim 10
Dependent Claim
16 words
The process of claim 7 where the α-aminophosphonic acids formed comprise those of the formula ##STR20##10.
Claim 11
Dependent Claim
16 words
The process of claim 1 where the nitrile m-toluonitrile and the phosphite ester is diethyl phosphite.
Claim 12
Dependent Claim
22 words
The process of claim 7 where the nitrile is m-toluonitrile, the phosphite ester is diethyl phosphite and the final product obtained is
References Cited (Backward Citations)
US2971019A
Cited
US3048613A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1980-01-25 | 1980-07-26 | 1981-01-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1984-01-25 | 1984-07-26 | 1985-01-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1988-01-25 | 1988-07-26 | 1989-01-25 | $7700.00 | Window Closed / Lapsed |