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US4021539A Expired / Lapsed US ⏱️ 0.0 years remaining

Skin treating cosmetic compositions containing N-polyhydroxyalkyl-amines

Assignee: Henkel AG and Co KGaA
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Filing: 1975-01-28
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Granted: 1977-05-03
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Expires: 1995-01-28
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Abstract

Abstract The present invention relates to compositions for the treatment of the skin containing up to 25% by weight of at least one N-polyhydroxyalkyl-amine of the formula <IMAGE> wherein R1 is hydrogen, lower alkyl, hydroxy-lower alkyl or aminoalkyl, as well as heterocyclic aminoalkyl, R is the same as R1 except that both cannot be hydrogen at the same time, R2 is -CH2OH or -COOH, m is the integer 3 or 4, and n is the integer O, or, when m is 3 and R2 is -CH2OH, 1; and the method of skin treatment therewith.

Inventors

  • 👤 Hinrich Moller
  • 👤 Rainer Osberghaus
  • 👤 Christian Gloxhuber
  • 👤 Siegfried Braig

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 10:48
CPC Classifications
A; A61; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/41; A61K8/02; A61K8/0212; A61Q; A61Q17/00; A61Q19/00; A61Q17/04; A61Q19/002; A61Q19/005

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 303 words
A cosmetic composition for maintaining or restoring a certain hygroscopicity in the skin for the protection of the skin of warm-blooded animals consisting essentially of an aqueous composition having a pH of between 5 and 7 and containing from 1 to 20% by weight of at least one N-polyhydroxyalkyl-amine compound selected from the group consisting of (1) amines of the formula ##STR13## wherein R 1 is a member selected from the group consisting of hydrogen, alkyl having from 1 to 18 carbon atoms, hydroxyalkyl having from 2 to 6 carbon atoms, dihydroxyalkyl having from 3 to 6 carbon atoms, trihydroxyalkyl having from 4 to 6 carbon atoms, and ##STR14## wherein R 6 and R 7 are members selected from the group consisting of hydrogen, alkyl having from 1 to 12 carbon atoms, hydroxyalkyl having from 1 to 3 carbon atoms, with the proviso that only one of R 6 and R 7 can be hydrogen, and, when taken together with the nitrogen, pyridyl, piperazino, morpholino, furfuryl, pyrrolidino and hydroxyalkylpiperazino having from 1 to 3 carbon atoms in the alkyl, and q is an integer from 1 to 3, R is the same as R 1 , with the proviso that only one of R and R 1 can be hydrogen, and R and R 1 together with the nitrogen, are alkylpiperazino having from 1 to 3 carbon atoms in the alkyl or hydroxyalkylpiperazino having from 1 to 3 carbon atoms in the alkyl, R 2 is a member selected from the group consisting of --CH 2 OH and --COOH, m is the integer 3 or 4, and n is the integer 0, or, when m is 3 and R 2 is --CH 2 OH, 1, and (2) physiologically-compatible acid addition salts thereof, and the remainder to 100% by weight of inert cosmetic excipients.
Claim 2
Dependent Claim 303 words
A cosmetic composition for maintaining or restoring a certain hygroscopicity in the skin for the protection of the skin of warm-blooded animals consisting essentially of an aqueous composition having a pH of between 5 and 7 and containing from 1 to 20% by weight of at least one N-polyhydroxyalkyl-amine compound selected from the group consisting of (1) amines of the formula ##STR13## wherein R 1 is a member selected from the group consisting of hydrogen, alkyl having from 1 to 18 carbon atoms, hydroxyalkyl having from 2 to 6 carbon atoms, dihydroxyalkyl having from 3 to 6 carbon atoms, trihydroxyalkyl having from 4 to 6 carbon atoms, and ##STR14## wherein R 6 and R 7 are members selected from the group consisting of hydrogen, alkyl having from 1 to 12 carbon atoms, hydroxyalkyl having from 1 to 3 carbon atoms, with the proviso that only one of R 6 and R 7 can be hydrogen, and, when taken together with the nitrogen, pyridyl, piperazino, morpholino, furfuryl, pyrrolidino and hydroxyalkylpiperazino having from 1 to 3 carbon atoms in the alkyl, and q is an integer from 1 to 3, R is the same as R 1 , with the proviso that only one of R and R 1 can be hydrogen, and R and R 1 together with the nitrogen, are alkylpiperazino having from 1 to 3 carbon atoms in the alkyl or hydroxyalkylpiperazino having from 1 to 3 carbon atoms in the alkyl, R 2 is a member selected from the group consisting of --CH 2 OH and --COOH, m is the integer 3 or 4, and n is the integer 0, or, when m is 3 and R 2 is --CH 2 OH, 1, and (2) physiologically-compatible acid addition salts thereof, and the remainder to 100% by weight of inert cosmetic excipients.
Claim 3
Dependent Claim 24 words
The composition of claim 1 wherein said at least one N-polyhydroxyalkyl-amine compound is present in an amount of from 3 to 10% by weight.
Claim 4
Dependent Claim 9 words
The composition of claim 1 wherein R is hydrogen.
Claim 5
Dependent Claim 10 words
The composition of claim 1 wherein the pH is 6.
Claim 6
Dependent Claim 16 words
The composition of claim 1 wherein said aqueous composition is an aqueous emulsion including an emulsifier.
Claim 7
Dependent Claim 13 words
The composition of claim 1 wherein said aqueous composition is an after-shave lotion.
Claim 8
Dependent Claim 42 words
A process for maintaining or restoring a certain hygroscopicity in the skin for the protection of the skin of warm-blooded animals comprising topically applying to the skin a safe but effective amount as a moisturizing agent of the composition of claim 1.
Claim 9
Dependent Claim 223 words
A cosmetic composition for maintaining or restoring a certain hygroscopicity in the skin for the protection of the skin of warm-blooded animals consisting essentially of an aqueous composition having a pH of between 5 and 7 and containing from 1% to 20% by weight of at least one N-polyhydroxyalkyl-amine compound selected from the group consisting of (1) amines of the formula ##STR15## wherein R 1 is a member selected from the group consisting of alkyl having from 1 to 18 carbon atoms, hydroxyalkyl having from 2 to 6 carbon atoms, dihydroxyalkyl having from 3 to 6 carbon atoms, trihydroxyalkyl having from 4 to 6 carbon atoms, and ##STR16## wherein R 6 and R 7 are members selected from the group consisting of hydrogen, alkyl having from 1 to 12 carbon atoms, hydroxyalkyl having from 1 to 3 carbon atoms, with the proviso that only one of R 6 and R 7 can be hydrogen, and q is an integer from 1 to 3, R 2 is a member selected from the group consisting of --CH 2 OH and --COOH, m is the integer 3 or 4, and n is the integer 0, or, when m is 3 and R 2 is --CH 2 OH, 1, and (2) physiologically-compatible acid addition salts thereof, and the remainder to 100% by weight of inert cosmetic excipients.
Claim 10
Dependent Claim 223 words
A cosmetic composition for maintaining or restoring a certain hygroscopicity in the skin for the protection of the skin of warm-blooded animals consisting essentially of an aqueous composition having a pH of between 5 and 7 and containing from 1% to 20% by weight of at least one N-polyhydroxyalkyl-amine compound selected from the group consisting of (1) amines of the formula ##STR15## wherein R 1 is a member selected from the group consisting of alkyl having from 1 to 18 carbon atoms, hydroxyalkyl having from 2 to 6 carbon atoms, dihydroxyalkyl having from 3 to 6 carbon atoms, trihydroxyalkyl having from 4 to 6 carbon atoms, and ##STR16## wherein R 6 and R 7 are members selected from the group consisting of hydrogen, alkyl having from 1 to 12 carbon atoms, hydroxyalkyl having from 1 to 3 carbon atoms, with the proviso that only one of R 6 and R 7 can be hydrogen, and q is an integer from 1 to 3, R 2 is a member selected from the group consisting of --CH 2 OH and --COOH, m is the integer 3 or 4, and n is the integer 0, or, when m is 3 and R 2 is --CH 2 OH, 1, and (2) physiologically-compatible acid addition salts thereof, and the remainder to 100% by weight of inert cosmetic excipients.
Claim 11
Dependent Claim 11 words
The composition of claim 8 wherein said N-polyhydroxyalkyl-amine compound is N-(3-dimethylaminopropyl)-glucamine.

References Cited (Backward Citations)

US2703798A Cited
US2715123A Cited
US2808401A Cited
US2815339A Cited
US2815340A Cited
US2789976A Cited
US2936308A Cited
US2922784A Cited
US2970128A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-05-02 1980-11-01 1981-05-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-05-02 1984-11-01 1985-05-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-05-02 1988-11-01 1989-05-03 $7700.00 Window Closed / Lapsed

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