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US4046894A Expired / Lapsed US ⏱️ 0.0 years remaining

Certain barbituric acid derivatives used as anticonvulsant agents

Assignee: Colgate Palmolive Co
•
Filing: 1971-03-18
•
Granted: 1977-09-06
•
Expires: 1991-03-18
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Abstract

Abstract Various derivatives of barbituric acid and of diphenylhydantoin are described in which alkoxymethyl or benzyloxymethyl groups are attached to the nitrogen atoms of the rings. Therapeutic compositions containing these compounds and their use as anticonvulsant agents are described.

Inventors

  • 👤 Carlos M. Samour
  • 👤 Julius A. Vida

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-07 19:13
CPC Classifications
C; C07; C07D; C07D233/00; C07D233/54; C07D233/66; C07D233/72; C07D233/76; C07D233/78; C07D239/00; C07D239/02; C07D239/24; C07D239/28; C07D239/46; C07D239/60; C07D239/62

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 65 words
A method of treating convulsions in warm-blooded animals which comprises administering to said animals an amount sufficient to produce an anticonvulsant effect of a compound having the structure ##STR2## wherein R and R 1 are phenyl and ethyl respectively, or R and R 1 are individually ethyl, allyl or 2-pentyl and wherein R 2 and R 3 are individually methyl, ethyl, butyl, lauryl or benzyl.
Claim 2
Independent Claim 65 words
A method of treating convulsions in warm-blooded animals which comprises administering to said animals an amount sufficient to produce an anticonvulsant effect of a compound having the structure ##STR2## wherein R and R 1 are phenyl and ethyl respectively, or R and R 1 are individually ethyl, allyl or 2-pentyl and wherein R 2 and R 3 are individually methyl, ethyl, butyl, lauryl or benzyl.
Claim 3
Dependent Claim 24 words
A method according to claim 1 in which from about 5 to 500 mg. of said compound is administered to said warm blooded animal.
Claim 4
Dependent Claim 24 words
A method according to claim 1 in which from about 5 to 200 mg. of said compound is administered to said warm blooded animal.
Claim 5
Dependent Claim 13 words
A method according to claim 1 in which said compound is N,N'-dimethoxymethyl phenobarbital.
Claim 6
Dependent Claim 13 words
A method according to claim 1 in which said compound is N,N'-diethoxymethyl phenobarbital.

References Cited (Backward Citations)

US2344459A Cited
US3341512A Cited
US3663699A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-09-05 1981-03-07 1981-09-06 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-09-05 1985-03-07 1985-09-06 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-09-05 1989-03-07 1989-09-06 $7700.00 Window Closed / Lapsed

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