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US4056484A Expired / Lapsed US ⏱️ 0.0 years remaining

Stable blood plasma, process for preparing it and its use as comparative plasma in coagulation tests

Assignee: Siemens Healthcare Diagnostics GmbH Germany
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Filing: 1975-12-29
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Granted: 1977-11-01
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Expires: 1995-12-29
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Abstract

Abstract Lyophilized blood plasma under a protective gas wherein the protective gas contains at least 5% of carbon dioxide.

Inventors

  • 👤 Norbert Heimburger
  • 👤 Axel Sieber
  • 👤 Horst Schwinn

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-24 01:01
CPC Classifications
F; F26; F26B; F26B5/00; F26B5/04; F26B5/06; A; A01; A01N; A01N1/00; A01N1/10; A01N1/12; A01N1/122; A01N1/125; A61; A61K; A61K35/00; A61K35/12; A61K35/14; A61K35/16; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/96; G01N2496/00; G01N2496/05; Y; Y10; Y10T; Y10T436/00; Y10T436/10; Y10T436/106664; Y10T436/107497; Y10T436/108331

Claims Analysis

Total Claims: 5
Claim 1
Independent Claim 25 words
Lyophilized blood plasma containing an anti-coagulating agent and present in a sealed container under a protective gas containing at least 5 percent of carbon dioxide.
Claim 2
Dependent Claim 25 words
Lyophilized blood plasma containing an anti-coagulating agent and present in a sealed container under a protective gas containing at least 5 percent of carbon dioxide.
Claim 3
Dependent Claim 13 words
Lyophilized blood plasma as in claim 1 which additionally contains a colloid-stabilizing additive.
Claim 4
Dependent Claim 68 words
A method for making lyophilized blood plasma as in claim 1, which method comprises mixing fresh blood with an anticoagulating agent, centrifuging said mixture and separating the plasma component thereof, filling said plasma into a non-wettable container, freezing said plasma to form frozen plasma having a large surface area, lyophilizing said frozen plasma, evacuating said container, introducing said protective gas into said container, and then sealing said container.
Claim 5
Dependent Claim 54 words
In a method for determining a component of blood plasma by observing the coagulation behavior of a plasma sample to be tested and comparing this behavior with the coagulation behavior of a plasma of known characteristics, the improvement wherein said plasma of known characteristics is prepared from lyophilized blood plasma as in claim 1.

References Cited (Backward Citations)

US3466249A Cited
US3629142A Cited
US3682835A Cited
US3876375A Cited
US3876375B1 Cited
US3897363A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1980-10-31 1981-05-02 1981-11-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1984-10-31 1985-05-02 1985-11-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1988-10-31 1989-05-02 1989-11-01 $7700.00 Window Closed / Lapsed

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