US4072610A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Production of solutions
Assignee: Ingerthorpe Holdings Ltd
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Filing: 1975-05-01
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Granted: 1978-02-07
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Expires: 1995-05-01
Abstract
Abstract This invention relates to the production of aqueous solutions of desired concentration for medical purposes which comprises passing water through a reverse osmosis column capable of retaining 100% of pyrogenic materials; and subsequently, in either order, passing the water through a sterilizer capable of eliminating 100% of bacterial material, and admixing, in suitable ratio, the water with a desired material or with a solution of such material of higher concentration than desired to produce said desired concentration solution.
Inventors
- 👤 James G. Gow
- 👤 Alan G. England
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 22:18
CPC Classifications
A; A61; A61L; A61L2/00; A61L2/02; A61L2/04; A61L2/022; B; B01; B01D; B01D61/00; B01D61/02; B01D61/025; A61L2103/00; A61L2103/05
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
179 words
An apparatus for the production of an aqueous solution of desired concentration for medical purposes, which comprises a first pump connectible to a source of water, a reverse osmosis column connected to said first pump, said reverse osmosis column being capable of retaining 100% of bacterial material; a heat steriliser capable of eliminating 100% of bacterial material; a proportioning pump for admixing the pyrogen-free water with a desired material or with a solution of such material of higher concentration than desired to provide said desired concentration; first fluid flow means connecting an outlet of said reverse osmosis column to the proportioning pump; second fluid flow means connecting an outlet of said proportioning pump to an inlet of said steriliser; a filter between the outlet from the reverse osmosis column and the inlet to the steriliser and including means for measuring the pressure differential between the two sides of the filter; and a device for switching off the apparatus in the event that during operation the pressure differential between the two sides of the filter varies from its normal range.
Claim 2
Independent Claim
179 words
An apparatus for the production of an aqueous solution of desired concentration for medical purposes, which comprises a first pump connectible to a source of water, a reverse osmosis column connected to said first pump, said reverse osmosis column being capable of retaining 100% of bacterial material; a heat steriliser capable of eliminating 100% of bacterial material; a proportioning pump for admixing the pyrogen-free water with a desired material or with a solution of such material of higher concentration than desired to provide said desired concentration; first fluid flow means connecting an outlet of said reverse osmosis column to the proportioning pump; second fluid flow means connecting an outlet of said proportioning pump to an inlet of said steriliser; a filter between the outlet from the reverse osmosis column and the inlet to the steriliser and including means for measuring the pressure differential between the two sides of the filter; and a device for switching off the apparatus in the event that during operation the pressure differential between the two sides of the filter varies from its normal range.
Claim 3
Dependent Claim
23 words
An apparatus as claimed in claim 1 in which the proportioning pump has a delivery rate of up to 11/2 liters per minute.
Claim 4
Dependent Claim
34 words
An apparatus as claimed in claim 1 in which the reverse osmosis column has a semi-permeable membrane which prevents passage of materials having a molecular weight of 2,000 and above and preferably above 200.
Claim 5
Dependent Claim
72 words
Apparatus as claimed in claim 1 wherein the proportioning pump comprises a variable ratio mix pump for mixing said pyrogen free water with a solution of higher concentration than desired to produce said desired concentration solution, and a sensor connected downstream of the proportioning pump for monitoring the concentration of the proportioning pump output solution, the sensor being operable to control the operation of the pump in dependence upon the monitored concentration.
Claim 6
Dependent Claim
25 words
Apparatus as claimed in claim 4 further comprising means for adjusting the temperature of the sterilised, admixed solution of desired concentration to substantially 80° C.
Claim 7
Dependent Claim
64 words
Apparatus as claimed in claim 5 wherein said temperature adjustment means comprises a heat exchanger having two flow paths one of which is connected upstream of said pre-heater and the second of which is connected downstream of said main steriliser, and a heater connected downstream of said second flow path and said proportioning system for heating the sterilised, admixed solution to substantially 80° C.
Claim 8
Dependent Claim
29 words
Apparatus as claimed in claim 1 further comprising injection means operable responsively to deactivation of the apparatus to displace water in the apparatus with a fluid for killing bacteria.
Claim 9
Dependent Claim
20 words
Apparatus as claimed in claim 7 wherein said injection means is an injection pump and said fluid is formalin solution.
Claim 10
Dependent Claim
68 words
Apparatus as claimed in claim 1 whose output is connected to a bottling machine for bottling said aqueous solution, an overflow of the bottling machine being connected to a second input of the apparatus for feeding overflow solution into said apparatus upstream of the steriliser, the second input being connected to the steriliser upstream thereof by way of cooling means for reducing the temperature of said overflow solution.
Claim 11
Independent Claim
200 words
An apparatus for the production of an aqueous solution of desired concentration for medical purposes, which comprises a first pump connectible to a source of water, a reverse osmosis column connected to said first pump, said reverse osmosis column being capable of retaining 100% of pyrogenic material; a heat steriliser capable of eliminating 100% of bacterial material; a proportioning pump for admixing the pyrogen-free water with a desired material or with a solution of such material of higher concentration than desired to provide said desired concentration; first fluid flow means connecting an outlet of said reverse osmosis column to one of the heat steriliser and the proportioning pump; second fluid flow means connecting an outlet of said one of the heat steriliser and the proportioning pump to an inlet of the other of the heat steriliser and the proportioning pump; a filter between the outlet from the reverse osmosis column and the inlet to the steriliser and including means for measuring the pressure differential between the two sides of the filter; and a device for switching off the apparatus in the event that during operation the pressure differential between the two sides of the filter varies from its normal range.
Claim 12
Independent Claim
200 words
An apparatus for the production of an aqueous solution of desired concentration for medical purposes, which comprises a first pump connectible to a source of water, a reverse osmosis column connected to said first pump, said reverse osmosis column being capable of retaining 100% of pyrogenic material; a heat steriliser capable of eliminating 100% of bacterial material; a proportioning pump for admixing the pyrogen-free water with a desired material or with a solution of such material of higher concentration than desired to provide said desired concentration; first fluid flow means connecting an outlet of said reverse osmosis column to one of the heat steriliser and the proportioning pump; second fluid flow means connecting an outlet of said one of the heat steriliser and the proportioning pump to an inlet of the other of the heat steriliser and the proportioning pump; a filter between the outlet from the reverse osmosis column and the inlet to the steriliser and including means for measuring the pressure differential between the two sides of the filter; and a device for switching off the apparatus in the event that during operation the pressure differential between the two sides of the filter varies from its normal range.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-02-06 | 1981-08-08 | 1982-02-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-02-06 | 1985-08-08 | 1986-02-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-02-06 | 1989-08-08 | 1990-02-07 | $7700.00 | Window Closed / Lapsed |