US4072679A
Expired / Lapsed
US
⏱️ 0.0 years remaining
1,4- AND 4,10-DIHYDRO-4-OXO-PYRIMIDO (1,2-A)-benzimidazole-3-carboxylic acids, esters and amides
Assignee: ER Squibb and Sons LLC
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Filing: 1976-06-15
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Granted: 1978-02-07
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Expires: 1996-06-15
Abstract
Abstract New derivatives, and their salts, of 1,4- and 4,10-dihydro-4-oxo-pyrimido[1,2-a]benzimidazole-3-carboxylic acids, esters and carboxamides have the general formulas ##STR1## They are useful as central nervous system depressants and anti-inflammatory agents.
Inventors
- 👤 Theodor Denzel
- 👤 Hans Hoehn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 02:22
CPC Classifications
C; C07; C07D; C07D487/00; C07D487/02; C07D487/04
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
75 words
A compound of the formula ##STR93## wherein R 1 is hydrogen, lower alkyl, phenyl-lower alkyl or lower alkyl ##STR94## R 2 is hydrogen or lower alkyl; R 3 is hydroxy, lower alkoxy or ##STR95## R 4 and R 5 each is lower alkyl; R 6 and R 7 each is hydrogen, lower alkyl, phenyl, substituted phenyl wherein the phenyl substituent is halo, lower alkyl or lower alkoxy or phenyllower alkyl; and physiologically acceptable salts thereof.
Claim 2
Dependent Claim
75 words
A compound of the formula ##STR93## wherein R 1 is hydrogen, lower alkyl, phenyl-lower alkyl or lower alkyl ##STR94## R 2 is hydrogen or lower alkyl; R 3 is hydroxy, lower alkoxy or ##STR95## R 4 and R 5 each is lower alkyl; R 6 and R 7 each is hydrogen, lower alkyl, phenyl, substituted phenyl wherein the phenyl substituent is halo, lower alkyl or lower alkoxy or phenyllower alkyl; and physiologically acceptable salts thereof.
Claim 3
Dependent Claim
28 words
A compound of the formula ##STR96## wherein R 1 , R 2 and R 3 have the same meaning as in claim 1, and physiologically acceptable salts thereof.
Claim 4
Dependent Claim
11 words
A compound as in claim 1 wherein R 2 is hydrogen.
Claim 5
Dependent Claim
11 words
A compound as in claim 2 wherein R 2 is hydrogen.
Claim 6
Dependent Claim
33 words
A compound as in claim 1 wherein R 1 is lower alkyl; R 2 is hydrogen or lower alkyl; R 3 is hydroxy, lower alkoxy or lower alkylamino, and physiologically acceptable salts thereof.
Claim 7
Dependent Claim
33 words
A compound as in claim 2 wherein R 1 is lower alkyl; R 2 is hydrogen or lower alkyl; R 3 is hydroxy, lower alkoxy or lower alkylamino, and physiologically acceptable salts thereof.
Claim 8
Dependent Claim
12 words
A compound as in claim 1 wherein R 3 is lower alkoxy.
Claim 9
Dependent Claim
12 words
A compound as in claim 1 wherein R 3 is lower alkylamino.
Claim 10
Dependent Claim
22 words
A compound as in claim 1 wherein R 1 is lower alkyl; R 2 is hydrogen and R 3 is lower alkoxy.
Claim 11
Dependent Claim
22 words
A compound as in claim 1 wherein R 1 is lower alkyl; R 2 is hydrogen and R 3 is lower alkylamino.
Claim 12
Dependent Claim
22 words
A compound as in claim 2 wherein R 1 is lower alkyl; R 2 is hydrogen and R 3 is lower alkoxy.
Claim 13
Dependent Claim
22 words
A compound as in claim 2 wherein R 1 is lower alkyl; R 2 is hydrogen and R 3 is lower alkylamino.
Claim 14
Dependent Claim
20 words
A compound as in claim 1 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is hydroxy.
Claim 15
Dependent Claim
20 words
A compound as in claim 1 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is ethoxy.
Claim 16
Dependent Claim
20 words
A compound as in claim 1 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is butylamino.
Claim 17
Dependent Claim
20 words
A compound as in claim 2 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is hydroxy.
Claim 18
Dependent Claim
20 words
A compound as in claim 2 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is ethoxy.
Claim 19
Dependent Claim
20 words
A compound as in claim 2 wherein R 1 is ethyl; R 2 is hydrogen and R 3 is butylamino.
References Cited (Backward Citations)
US3538086A
Cited
US3414574A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-02-06 | 1981-08-08 | 1982-02-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-02-06 | 1985-08-08 | 1986-02-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-02-06 | 1989-08-08 | 1990-02-07 | $7700.00 | Window Closed / Lapsed |