US4086221A
Expired / Lapsed
US
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Polypeptides and process for producing the same
Assignee: Asahi Kasei Corp
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Filing: 1976-05-03
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Granted: 1978-04-25
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Expires: 1996-05-03
Abstract
Abstract Polypeptides of the formula <IMAGE> Gly-A10-A11-A12-Gln-A14-A15-A16-Lys-A18- A19-Thr-A21-Pro-A23-Thr-A25-A26-Gly-A28- Gly-A30-Pro-NH2 wherein A1 is Ser or Gly, A7 is Val or Met, A10 is Lys or Thr, A11 is Leu or Tyr, A12 is Ser or Thr, A14 is Glu or Asp, A15 is Leu or Phe, A16 is His or Asn, A18 is Leu or Phe, A19 is Gln or His, A21 is Tyr or Phe, A23 is Arg or Gln, A25 is Asp or Asn or Ala, A26 is Val or Thr or Ile, A28 is Ala or Ser or Val, and A30 is Thr or Val or Ala, and pharmaceutically acceptable acid addition salts and complexes, have serum calcium reducing activity.
Inventors
- 👤 Shumpei Sakakibara
- 👤 Tadanori Morikawa
- 👤 Eisuke Munekata
- 👤 Terutoshi Kimura
- 👤 Yasuo Nakagawa
- 👤 Toshiharu Noda
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 14:10
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/575; C07K14/585; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
44 words
A polypeptide selected from the group consisting of a compound of the formula ##STR17## wherein A 25 is Asp or Asn, A 26 is Val or Thr and A 28 is Ala or Ser, and a pharmaceutically acceptable acid addition salt or complex thereof.
Claim 2
Dependent Claim
44 words
A polypeptide selected from the group consisting of a compound of the formula ##STR17## wherein A 25 is Asp or Asn, A 26 is Val or Thr and A 28 is Ala or Ser, and a pharmaceutically acceptable acid addition salt or complex thereof.
Claim 3
Dependent Claim
6 words
A polypeptide of the formula ##STR18##
Claim 4
Dependent Claim
6 words
A polypeptide of the formula ##STR18##
Claim 5
Dependent Claim
6 words
A polypeptide of the formula ##STR19##
Claim 6
Dependent Claim
6 words
A polypeptide of the formula ##STR19##
References Cited (Backward Citations)
US3798203A
Cited
US3891614A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-04-24 | 1981-10-24 | 1982-04-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-04-24 | 1985-10-24 | 1986-04-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-04-24 | 1989-10-24 | 1990-04-25 | $7700.00 | Window Closed / Lapsed |