Process for the preparation of carbamate derivatives

Abstract

Abstract A process for the preparation of a compound of the formula: ##STR1## wherein R 1 is alkyl, alkyl substituted by halogen, alkyl substituted by alkoxy, aryl, aryl substituted by halogen, aryl substituted by alkyl, aryl substituted by alkoxy, aralkyl, aralkyl substituted by alkoxy, cycloalkyl, cycloalkyl substituted by halogen, cycloalkyl substituted by alkyl or cycloalkyl substituted by alkoxy, and R 2 is an aromatic group, an aromatic group substituted by alkyl, an aromatic group substituted by halogen, an aromatic group substituted by alkoxy, a heteroaromatic group, a heteroaromatic group substituted by alkyl, a heteroaromatic group substituted by halogen, or a heteroaromatic group substituted by alkoxy, by the reaction of phosgene with a phenol of the formula: R.sup.2 -OH and further by the reaction of a primary amine of the formula: R'--NH.sub.2, reacting all three of the abovementioned reactants solution in a common water-immiscible organic solvent in the same reaction vessel at the same time in the presence of an acid binding agent to yield the compound of formula ##STR2##

Inventors

• 👤 Geza Toth
• 👤 Istvan Toth
• 👤 Tibor Montay

Bibliographic Details