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US4123512A Expired / Lapsed US ⏱️ 0.0 years remaining

Antibacterial oral composition

Assignee: Colgate Palmolive Co
•
Filing: 1977-04-25
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Granted: 1978-10-31
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Expires: 1997-04-25
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Abstract

Abstract An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a polymeric polyphosphonic compound, such as polyallyl bis-(phosphonomethylene) amine acid and salts thereof.

Inventors

  • 👤 Abdul Gaffar

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-11-02 10:10
CPC Classifications
A; A61; A61Q; A61Q11/00; A61K; A61K8/00; A61K8/18; A61K8/30; A61K8/40; A61K8/41; A61K8/416; A61K8/43; A61K8/55; A61K8/72; A61K8/81; A61K8/817; A61K2800/00; A61K2800/40; A61K2800/52

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 58 words
An oral composition comprising an oral vehicle, an amidine antibacterial antiplaque agent tending to stain dental surfaces and a water soluble polymeric polyphosphonic compound having the recurring group: ##STR17## wherein X is selected from the group consisting of hydrogen and an orally acceptable cation and said compound antistain additive has a molecular weight of at least about 2,000.
Claim 2
Dependent Claim 58 words
An oral composition comprising an oral vehicle, an amidine antibacterial antiplaque agent tending to stain dental surfaces and a water soluble polymeric polyphosphonic compound having the recurring group: ##STR17## wherein X is selected from the group consisting of hydrogen and an orally acceptable cation and said compound antistain additive has a molecular weight of at least about 2,000.
Claim 3
Dependent Claim 27 words
The oral composition of claim 1 wherein said polymeric polyphosphonic compound is in the form of its sodium salt and has a molecular weight of about 2,000.
Claim 4
Dependent Claim 50 words
The oral composition of claim 1 wherein said antibacterial antiplaque agent is present in amount to provide about 0.001% to about 15% by weight based on the free base form of said agent and said polymeric polyphosphonic compound is present in amount of about 0.01% to about 10% by weight.
Claim 5
Dependent Claim 46 words
The oral composition of claim 3 whereim said antibacterial antiplaque agent is present in amount of about 0.01% to about 5% by weight based on the free base form of said agent and said polymeric polyphosphonic compound is present in a molar excess to said agent.
Claim 6
Dependent Claim 15 words
The oral composition of claim 3 wherein said antibacterial antiplaque agent is a substituted guanidine.
Claim 7
Dependent Claim 30 words
The oral composition of claim 5 wherein said antibacterial antiplaque agent is a pharmaceutically acceptable water soluble salt of an agent selected from the group consisting of chlorhexidine and alexidine.
Claim 8
Dependent Claim 20 words
The oral composition of claim 6 wherein said antibacterial antiplaque agent is a pharmaceutically acceptable water soluble salt of chlorhexidine.
Claim 9
Dependent Claim 26 words
The oral composition of claim 1 wherein said vehicle is an aqueous-alcohol and said composition is a mouthwash of pH of about 4.5 to about 10.
Claim 10
Dependent Claim 39 words
The oral composition of claim 1 wherein said vehicle comprises a liquid vehicle and a gelling agent and a dentally acceptable polishing material is present and said composition is a toothpaste of pH of about 4.5 to about 10.

References Cited (Backward Citations)

US3429963A Cited
DE2156491A1 Cited
US3937805A Cited
FR2159507B1 Cited
US3934002A Cited
US3959458A Cited
US4025616A Cited
US3956480A Cited
FR2280362A2 Cited
US4042679A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1981-10-30 1982-05-01 1982-10-31 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1985-10-30 1986-05-01 1986-10-31 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1989-10-30 1990-05-01 1990-10-31 $7700.00 Window Closed / Lapsed

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