US4137231A
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US
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Process for the isolation of 2-hydroxymethyl-3,4,5-trihydroxypiperidine from plant material
Assignee: Nippon Shinyaku Co Ltd
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Filing: 1976-12-20
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Granted: 1979-01-30
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Expires: 1996-12-20
Abstract
Abstract 2-Hydroxymethyl-3,4,5-trihydroxypiperidine is obtained from the mulberry plant through extraction, optionally with further purification through ion exchange or chromatographic treatment.
Inventors
- 👤 Hiromu Murai
- 👤 Hiroshi Enomoto
- 👤 Yoshiaki Yoshikuni
- 👤 Tatsuhiko Kono
- 👤 Masahiro Yagi
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 07:10
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/46; A; A61; A61P; A61P3/00; A61P3/08
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
28 words
The process which comprises extracting 2-hydroxymethyl-3,4,5-trihydroxypiperidine from plant material of the Morus genus with water or a polar organic solvent and isolating the 2-hydroxymethyl-3,4,5-trihydroxypiperidine from the resultant extract.
Claim 2
Dependent Claim
28 words
The process which comprises extracting 2-hydroxymethyl-3,4,5-trihydroxypiperidine from plant material of the Morus genus with water or a polar organic solvent and isolating the 2-hydroxymethyl-3,4,5-trihydroxypiperidine from the resultant extract.
Claim 3
Dependent Claim
17 words
The process according to claim 1 wherein said extract is chromatographed on an activated carbon-celite silica gel.
Claim 4
Dependent Claim
16 words
The process according to claim 1 wherein said extract is treated with an ion exchange resin.
Claim 5
Dependent Claim
25 words
The process according to claim 1 wherein said plant material is extracted with at least one member selected from the group of water and methanol.
Claim 6
Dependent Claim
28 words
The process according to claim 4 wherein said extracts are washed with an organic solvent of less polarity than methanol to remove any components soluble in ethyl acetate.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-01-29 | 1982-07-31 | 1983-01-30 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-01-29 | 1986-07-31 | 1987-01-30 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-01-29 | 1990-07-31 | 1991-01-30 | $7700.00 | Window Closed / Lapsed |