US4166900A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Preparation of refined olefin/maleic acid copolymers
Assignee: Monsanto Co
•
Filing: 1977-12-23
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Granted: 1979-09-04
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Expires: 1997-12-23
Abstract
Abstract {PG,1 Olefin/maleic acid copolymer is refined to pharmaceutical quality by use of dichloroethane to remove contaminants, as by precipitating from solution with dichloroethane.
Inventors
- 👤 Robert A. Heimsch
- 👤 John H. Johnson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-09 03:23
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/74; A61K31/765; A61P; A61P3/00; A61P3/06; C; C08; C08F; C08F6/00; C08F6/06; C08F6/10; C08F8/00; C08F8/12; C08F2810/00; C08F2810/50; Y; Y10; Y10S; Y10S526/00; Y10S526/936
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
25 words
A method of refining α-olefin/maleic acid copolymer in which the olefin is a higher olefin, which comprises selectively precipitating such copolymer from solution with dichloroethane.
Claim 2
Independent Claim
25 words
A method of refining α-olefin/maleic acid copolymer in which the olefin is a higher olefin, which comprises selectively precipitating such copolymer from solution with dichloroethane.
Claim 3
Dependent Claim
13 words
The method of claim 1 in which said solution comprises octadecene-1/maleic acid copolymer.
Claim 4
Dependent Claim
14 words
The method of claim 1 in which said solution comprises said copolymer and acetone.
Claim 5
Dependent Claim
24 words
The method of claim 1 in which the dichloroethane is employed in about 3 to about 12 weight parts per weight part of solution.
Claim 6
Dependent Claim
20 words
The method of claim 4 in which the solution comprises about 30 l to about 60% by weight of copolymer.
Claim 7
Dependent Claim
27 words
The method of claim 1 in which the olefin has about 10 to about 22 carbon atoms and the solution is filtered prior to precipitating such polymer.
Claim 8
Independent Claim
41 words
A method of preparing a refined higher αolefin/maleic acid copolymer which comprises hydrolyzing a higher α-olefin/maleic anhydride copolymer, dissolving the hydrolyzed copolymer in a solvent, precipitating the polymer from the resulting solution with dichloroethane, and separating the polymer from the dichloroethane.
Claim 9
Independent Claim
41 words
A method of preparing a refined higher αolefin/maleic acid copolymer which comprises hydrolyzing a higher α-olefin/maleic anhydride copolymer, dissolving the hydrolyzed copolymer in a solvent, precipitating the polymer from the resulting solution with dichloroethane, and separating the polymer from the dichloroethane.
Claim 10
Dependent Claim
18 words
The method of claim 7 in which the maleic anhydride copolymer is hydrolyzed in aqueous sodium chloride solution.
Claim 11
Dependent Claim
13 words
The method of claim 7 in which the polymer is separated by filtration.
Claim 12
Dependent Claim
13 words
The process of claim 7 in which the polymer is separated by centrifugation.
Claim 13
Dependent Claim
19 words
The method of claim 8 in which the polymer after separation is treated with water, separated therefrom, and dried.
Claim 14
Dependent Claim
17 words
The method of claim 11 in which the drying is controlled to prevent dehydration to the anhydride.
Claim 15
Independent Claim
38 words
The method of refining higher α-olefin/maleic acid copolymer which comprises providing such copolymer in solid-liquid contact with dichloroethane, and separating the solid copolymer from the liquid dichloroethane containing dissolved materials which had been present in the copolymer material.
Claim 16
Independent Claim
38 words
The method of refining higher α-olefin/maleic acid copolymer which comprises providing such copolymer in solid-liquid contact with dichloroethane, and separating the solid copolymer from the liquid dichloroethane containing dissolved materials which had been present in the copolymer material.
Claim 17
Dependent Claim
21 words
The method of claim 13 in which the copolymer in finely divided form is slurried with the dichloroethane prior to separation.
Claim 18
Dependent Claim
13 words
The method of claim 13 in which the copolymer is washed with dichloroethane.
Claim 19
Dependent Claim
15 words
The method of claim 13 in which the copolymer and dichloroethane are separated by filtration.
Claim 20
Dependent Claim
60 words
A refined pharmaceutical grade higher α-olefin/maleic acid copolymer of high molecular weight with heterogeneous molecular weight distribution characterized by the low amount present of low molecular weight polymer removable by functional precipitation from solution and less than 0.1% of molecules of less than 2000 molecular weight and no more than 400 parts per million of α-olefin or maleic acid content.
Claim 21
Dependent Claim
60 words
A refined pharmaceutical grade higher α-olefin/maleic acid copolymer of high molecular weight with heterogeneous molecular weight distribution characterized by the low amount present of low molecular weight polymer removable by functional precipitation from solution and less than 0.1% of molecules of less than 2000 molecular weight and no more than 400 parts per million of α-olefin or maleic acid content.
Claim 22
Dependent Claim
11 words
The polymer of claim 17 in which the α-olefin is octadecene-1.
Claim 23
Dependent Claim
27 words
The polymer of claim 17 in which the copolymer has a particle size in which at least 70% of particles have a maximum dimension of 0.043 mm.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-09-03 | 1983-03-05 | 1983-09-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-09-03 | 1987-03-05 | 1987-09-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-09-03 | 1991-03-05 | 1991-09-04 | $7700.00 | Window Closed / Lapsed |