US4178463A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for making 4-aminohex-5-enoic acid
Assignee: Merrell Toraude et Cie
•
Filing: 1978-01-30
•
Granted: 1979-12-11
•
Expires: 1998-01-30
Abstract
Abstract Novel compounds of the following general formula are useful in the preparation of 4-aminohex-5-enoic acid and 4-aminohex-5-ynoic acid which are useful pharmacological agents: ##STR1## wherein R 1 is hydroxy, amino, or tert-butoxy.
Inventors
- 👤 Maurice W. Gittos
- 👤 Gerard J. Letertre
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-01 20:01
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/18; C07D207/22; C07D207/24; C07D207/26; C07D207/273; C07D207/277; C07D319/00; C07D319/04; C07D319/08
Claims Analysis
Total Claims: 3
Claim 1
Independent Claim
78 words
A process for the preparation of 4-aminohex-5-enoic acid or salt thereof which comprises treating a pyrrolidone compound of the formula ##STR11## wherein R 1 is hydroxy, amino, or tertiary-butoxy with an excess of a strong acid, optionally preceded by treatment with an excess of a strong base, at about 100° to 150° C. for about 2 to 24 hours followed by treatment with base or application to an acid ion exchange resin when the free base is desired.
Claim 2
Dependent Claim
78 words
A process for the preparation of 4-aminohex-5-enoic acid or salt thereof which comprises treating a pyrrolidone compound of the formula ##STR11## wherein R 1 is hydroxy, amino, or tertiary-butoxy with an excess of a strong acid, optionally preceded by treatment with an excess of a strong base, at about 100° to 150° C. for about 2 to 24 hours followed by treatment with base or application to an acid ion exchange resin when the free base is desired.
Claim 3
Dependent Claim
61 words
The process of claim 1 which comprises treating a pyrrolidone compound of the formula ##STR12## wherein R 1 is hydroxy, amino or tertiary-butoxy with an excess of a strong acid at about 100° to 150° C. for about 2 to 24 hours followed by treatment with base or application to an acid ion exchange resin when the free base is desired.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-10 | 1983-06-11 | 1983-12-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-10 | 1987-06-11 | 1987-12-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-10 | 1991-06-11 | 1991-12-11 | $7700.00 | Window Closed / Lapsed |