US4179434A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Amino acid derivatives
Assignee: ER Squibb and Sons LLC
•
Filing: 1978-06-29
•
Granted: 1979-12-18
•
Expires: 1998-06-29
Abstract
Abstract New substituted acyl derivatives of amino acids which have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.
Inventors
- 👤 Miguel A. Ondetti
- 👤 Michael E. Condon
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-29 00:13
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/80; C07D211/84; C07D211/86; C07C; C07C327/00; C07D207/00; C07D207/02; C07D207/04; C07D207/10; C07D207/16; C07D207/46; C07D209/00; C07D209/02; C07D209/04; C07D209/10; C07D209/18; C07D209/20; C07D211/06; C07D211/36; C07D211/60; A; A61; A61K; A61K38/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
34 words
A compound of the formula ##STR14## wherein R 1 is hydrogen, lower alkanoyl, or amino (imino)methyl; R 2 is hydrogen, lower alkyl or phenyl-lower alkylene; and R 3 is hydrogen, lower alkanoyl, or benzoyl.
Claim 2
Dependent Claim
34 words
A compound of the formula ##STR14## wherein R 1 is hydrogen, lower alkanoyl, or amino (imino)methyl; R 2 is hydrogen, lower alkyl or phenyl-lower alkylene; and R 3 is hydrogen, lower alkanoyl, or benzoyl.
Claim 3
Dependent Claim
20 words
A compound as in claim 1 wherein R 2 and R 3 each is hydrogen and R 1 is amino(imino)methyl.
Claim 4
Dependent Claim
18 words
A compound as in claim 1 wherein R 1 , R 2 and R 3 each is hydrogen.
Claim 5
Dependent Claim
1 words
D-Cysteinyl-L-tryptophane.
Claim 6
Dependent Claim
1 words
D-Cysteinyl-L-tryptophane.
References Cited (Backward Citations)
US3799918A
Cited
US3959519A
Cited
DE2349707A1
Cited
JPS5124490A
Cited
US3952115A
Cited
US4064235A
Cited
US4024286A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-12-17 | 1983-06-18 | 1983-12-18 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-12-17 | 1987-06-18 | 1987-12-18 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-12-17 | 1991-06-18 | 1991-12-18 | $7700.00 | Window Closed / Lapsed |