US4182767A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Antihyperglycemic N-alkyl-3,4,5-trihydroxy-2-piperidine methanol
Assignee: Nippon Shinyaku Co Ltd
•
Filing: 1978-05-10
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Granted: 1980-01-08
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Expires: 1998-05-10
Abstract
Abstract 2-Hydroxymethyl-3,4,5-trihydroxy-N-alkylpiperidines and their acid addition salts are antihyperglycemic agents. A typical example is 2-hydroxymethyl-3,4,5-trihydroxy-N-methylpiperidine.
Inventors
- 👤 Hiromu Murai
- 👤 Hiroshi Enomoto
- 👤 Yoshiaki Aoyagi
- 👤 Yoshiaki Yoshikuni
- 👤 Masahiro Yagi
- 👤 Ichiro Shirahase
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-04 08:35
CPC Classifications
C; C07; C07D; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/46; A; A61; A61P; A61P3/00; A61P3/08
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
33 words
A compound selected from the group consisting of an N-alkylpiperidine of the formula: ##STR3## wherein R is alkyl of 1 to 4 carbon atoms, and the pharmaceutically acceptable nontoxic acid addition salts thereof.
Claim 2
Dependent Claim
33 words
A compound selected from the group consisting of an N-alkylpiperidine of the formula: ##STR3## wherein R is alkyl of 1 to 4 carbon atoms, and the pharmaceutically acceptable nontoxic acid addition salts thereof.
Claim 3
Dependent Claim
10 words
The compound according to claim 1 wherein R is methyl.
Claim 4
Dependent Claim
10 words
The compound according to claim 1 wherein R is ethyl.
Claim 5
Dependent Claim
10 words
The compound according to claim 1 wherein R is propyl.
Claim 6
Dependent Claim
10 words
The compound according to claim 1 wherein R is isobutyl.
Claim 7
Dependent Claim
27 words
The method of effecting an antihyperglycemic effect in humans and other animals which comprises administering thereto an antihyperglycemically effective amount of a compound according to claim 1.
Claim 8
Dependent Claim
22 words
A pharmaceutical composition comprising an antihyperglycemically effective amount of a compound according to claim 1 in combination with a pharmaceutically acceptable carrier.
References Cited (Backward Citations)
US4065562A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-01-07 | 1983-07-09 | 1984-01-08 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-01-07 | 1987-07-09 | 1988-01-08 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-01-07 | 1991-07-09 | 1992-01-08 | $7700.00 | Window Closed / Lapsed |