US4199531A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Intermediates for the production of quinones
Assignee: Takeda Pharmaceutical Co Ltd
•
Filing: 1977-10-11
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Granted: 1980-04-22
•
Expires: 1997-10-11
Abstract
Abstract A novel method for producing hydroquinone and quinone derivatives by a regio- and stereo-specific coupling reaction of hydroquinone derivative having a terminal activated (poly)prenyl side chain with a prenyl derivative. This method can provide in good yield various hydroquinone and quinone derivatives having any prenyl length of the side chain.
Inventors
- 👤 Shinji Terao
- 👤 Kaneyoshi Kato
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-28 23:47
CPC Classifications
C; C07; C07D; C07D303/00; C07D303/02; C07D303/12; C07D303/18; C07D303/20; C07D303/22; C07C; C07C317/00; C07C317/16; C07C317/18; C07C37/00; C07C37/01; C07C37/055; C07C46/00; C07C46/02; C07C46/06; C07C46/10; C07C50/00; C07C50/26; C07C50/28; C07D303/24; C07D303/32
Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
46 words
A compound of the formula: ##STR33## wherein R 1 is methoxy, Z is a protective group capable of protecting a hydroxyl group, A is halogen, arylthio, arylsulfinyl or arylsulfonyl, wherein aryl is phenyl or p-methylphenyl and n is an integer of from 1 to 9, inclusive.
Claim 2
Dependent Claim
46 words
A compound of the formula: ##STR33## wherein R 1 is methoxy, Z is a protective group capable of protecting a hydroxyl group, A is halogen, arylthio, arylsulfinyl or arylsulfonyl, wherein aryl is phenyl or p-methylphenyl and n is an integer of from 1 to 9, inclusive.
Claim 3
Dependent Claim
10 words
The compound according to claim 1, wherein A is halogen.
Claim 4
Dependent Claim
13 words
The compound according to claim 1, wherein A is arylthio, arylsulfinyl or arylsulfonyl.
Claim 5
Dependent Claim
10 words
The compound according to claim 3, wherein A is arylsulfonyl.
Claim 6
Dependent Claim
11 words
The compound according to claim 4, wherein the arylsulfonyl is p-toluenesulfonyl.
Claim 7
Dependent Claim
11 words
The compound according to claim 1, wherein R 1 is methoxy.
Claim 8
Dependent Claim
16 words
The compound according to claim 1, wherein the protective group is methyl, methoxymethyl, ethoxymethyl or benzyl.
Claim 9
Dependent Claim
14 words
The compound according to claim 7, wherein the protective group is ethoxymethyl or benzyl.
Claim 10
Dependent Claim
11 words
The compound according to claim 1, which is 28'-chloroubiquinol-7 dibenzyl ether.
Claim 11
Dependent Claim
11 words
The compound according to claim 1, which is 28'-(p-toluenesulfonyl)-ubiquinol-7 dibenzyl ether.
Claim 12
Dependent Claim
11 words
The compound according to claim 1, which is 4'-chloroubiquinol-1 dibenzyl ether.
Claim 13
Dependent Claim
11 words
The compound according to claim 1, which is 4'-bromoubiquinol-1 dibenzyl ether.
Claim 14
Dependent Claim
10 words
The compound according to claim 1, which is 4'-bromoubiquinol-1 bis(ethoxymethyl)ether.
Claim 15
Dependent Claim
11 words
The compound according to claim 1, which is 4'-(p-toluenesulfonyl)-ubiquinol-1 dibenzyl ether.
References Cited (Backward Citations)
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US3781313A
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US4038323A
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GB1396622A
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JPS4942627A
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US3960967A
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US4089873A
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-04-22 | 1983-10-22 | 1984-04-22 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-04-22 | 1987-10-22 | 1988-04-22 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-04-22 | 1991-10-22 | 1992-04-22 | $7700.00 | Window Closed / Lapsed |