US4206358A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Technetium-99 generators
Assignee: Australian Atomic Energy Commission
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Filing: 1978-10-16
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Granted: 1980-06-03
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Expires: 1998-10-16
Abstract
Abstract A generator for liquid containing 99m Tc has an adsorbant bed of alumina, zirconia or the like and has associated therewith a quantity of an electron scavenging compound of a rare earth, silver or gold so as to maintain elution efficiency during the working life of the generator. The compound may be a rare earth oxide such as ceric oxide typically present as a coating on alumina particles in an amount of about 0.1% by weight or a compound such as silver chloride present in quantities typically of about 5%. The eluant may be sodium or potassium perchlorate in water.
Inventors
- 👤 Ralph W. Matthews
- 👤 Rex E. Boyd
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 02:25
CPC Classifications
G; G21; G21G; G21G1/00; G21G1/04; G21G4/00; G21G4/04; G21G4/06; G21G4/08; G21G1/0005
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
117 words
In an isotope generator for the production of liquids containing 99m Tc comprising: (a) a container having a liquid inlet and a liquid outlet to permit the generator to be milked by the passage of a liquid eluant, (b) a quantity of adsorbant located in the container, (c) the adsorbant being a metal oxide having a relatively high affinity to a molybdenum-99 compound and a relatively low affinity to the technetium-99m daughter product of the molybdenum-99 compound, the improvement comprising: (d) an associated compound bound into the adsorbant and resistant to elution with said daughter product, said associated compound being an electron scavenging compound selected from the group consisting of compounds of rare earth, silver and gold.
Claim 2
Dependent Claim
117 words
In an isotope generator for the production of liquids containing 99m Tc comprising: (a) a container having a liquid inlet and a liquid outlet to permit the generator to be milked by the passage of a liquid eluant, (b) a quantity of adsorbant located in the container, (c) the adsorbant being a metal oxide having a relatively high affinity to a molybdenum-99 compound and a relatively low affinity to the technetium-99m daughter product of the molybdenum-99 compound, the improvement comprising: (d) an associated compound bound into the adsorbant and resistant to elution with said daughter product, said associated compound being an electron scavenging compound selected from the group consisting of compounds of rare earth, silver and gold.
Claim 3
Dependent Claim
36 words
An isotope generator according to claim 1, wherein said associated compound is a rare earth oxide with the rare earth in the four-valent form and selected from the group consisting of cerium, praseodymium, neodymium and terbium.
Claim 4
Dependent Claim
31 words
An isotope generator as claimed in claim 2, wherein said associated compound comprises ceric oxide present in a quantity in the range of 0.25% to 0.5% by weight of the adsorbant.
Claim 5
Dependent Claim
24 words
An isotope generator as claimed in claim 3, wherein said ceric oxide is present in an amount approximately 0.1% by weight of the adsorbant.
Claim 6
Dependent Claim
24 words
An isotope generator as claimed in claim 1, wherein said associated compound is selected from the group consisting of silver chloride and gold chloride.
Claim 7
Dependent Claim
25 words
As isotope generator as claimed in claim 5, wherein the associated compound is present in a quantity of approximately 5% by weight of the adsorbant.
Claim 8
Dependent Claim
28 words
An isotope generator as claimed in claim 1, wherein said adsorbant comprises particles of alumina and said associated compound is present as a coating on said alumina particles.
Claim 9
Dependent Claim
60 words
In an isotope generator for the production of liquids containing 99m Tc comprising an associated compound included with the adsorbant, the associated compound being a four-valent rare earth oxide of a rare earth selected from the group consisting of cerium, praseodymium, neodymium and terbium, said rare earth oxide being present in a quantity of approximately 0.1% by weight of adsorbant.
Claim 10
Dependent Claim
60 words
In an isotope generator for the production of liquids containing 99m Tc comprising an associated compound included with the adsorbant, the associated compound being a four-valent rare earth oxide of a rare earth selected from the group consisting of cerium, praseodymium, neodymium and terbium, said rare earth oxide being present in a quantity of approximately 0.1% by weight of adsorbant.
Claim 11
Dependent Claim
27 words
An isotope generator as claimed in claim 1 and further comprising a supply of aqueous eluant selected from the group consisting of sodium perchlorate and potassium perchlorate.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-06-03 | 1983-12-03 | 1984-06-03 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-06-03 | 1987-12-03 | 1988-06-03 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-06-03 | 1991-12-03 | 1992-06-03 | $7700.00 | Window Closed / Lapsed |