US4217345A
Expired / Lapsed
US
⏱️ 0.0 years remaining
3-0-(β-D-Glucuronopyranosyl)-soyasapogenol B
Assignee: Otsuka Pharmaceutical Co Ltd
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Filing: 1979-03-30
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Granted: 1980-08-12
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Expires: 1999-03-30
Abstract
Abstract 3-0-(β-D-Glucuronopyranosyl)-soyasapogenol B represented by the formula (I): ##STR1## and salts thereof and process for preparing the same are disclosed. The compound represented by the formula (I) and salts thereof have anticomplementary activity and are useful as therapeutic agents for autoimmune diseases, collagen diseases, and rheumatic diseases.
Inventors
- 👤 Masanao Shinohara
- 👤 Yoshimasa Nakano
- 👤 Hirotsugu Kaise
- 👤 Taketoshi Izawa
- 👤 Wasei Miyazaki
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-11-02 19:24
CPC Classifications
C; C12; C12N; C12N1/00; C12N1/14; C12N1/145; C07; C07H; C07H15/00; C07H15/20; C07H15/24; C07H15/256; A; A61; A61P; A61P13/00; A61P13/02; A61P15/00; A61P29/00; A61P37/00; C12P; C12P19/00; C12P19/44; C12P19/56; C12R; C12R2001/00; C12R2001/645
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
13 words
3-O-(β-D-glucuronopyranosyl)-soyasapogenol B represented by the formula (I): ##STR4## and pharmaceutically acceptable salts thereof.
Claim 2
Dependent Claim
13 words
3-O-(β-D-glucuronopyranosyl)-soyasapogenol B represented by the formula (I): ##STR4## and pharmaceutically acceptable salts thereof.
Claim 3
Dependent Claim
33 words
A pharmaceutical composition having anticomplementary activity in animals comprising a therapeutically effective amount of the soyasapogenol derivative of the formula (I) or a pharmaceutically acceptable salt thereof ##STR5## and a pharmaceutically acceptable carrier.
Claim 4
Dependent Claim
33 words
A pharmaceutical composition having anticomplementary activity in animals comprising a therapeutically effective amount of the soyasapogenol derivative of the formula (I) or a pharmaceutically acceptable salt thereof ##STR5## and a pharmaceutically acceptable carrier.
Claim 5
Dependent Claim
35 words
The composition according to claim 2, wherein the amount of the soyasaponin derivative or the pharmaceutically acceptable salt thereof is about 1 to 70% by weight based on the entire weight of the pharmaceutical composition.
Claim 6
Dependent Claim
29 words
An antinephritic pharmaceutical composition comprising a therapeutically effective amount of the soyasapogenol derivative of the formula (I) ##STR6## or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
Claim 7
Dependent Claim
29 words
An antinephritic pharmaceutical composition comprising a therapeutically effective amount of the soyasapogenol derivative of the formula (I) ##STR6## or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.
Claim 8
Dependent Claim
32 words
A method for treating nephritis, which comprises administering the composition according to claim 4 to a nephritic patient in a daily dose of about 0.5 to about 20 mg/kg of body weight.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1983-08-12 | 1984-02-11 | 1984-08-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1987-08-12 | 1988-02-11 | 1988-08-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1991-08-12 | 1992-02-11 | 1992-08-12 | $7700.00 | Window Closed / Lapsed |